ID A0A091JQM7_EGRGA Unreviewed; 505 AA.
AC A0A091JQM7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 19.
DE SubName: Full=Beta,beta-carotene 15,15'-monooxygenase {ECO:0000313|EMBL:KFP22892.1};
DE Flags: Fragment;
GN ORFNames=Z169_09453 {ECO:0000313|EMBL:KFP22892.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP22892.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP22892.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP22892.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787, ECO:0000256|RuleBase:RU003799}.
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DR EMBL; KK502392; KFP22892.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091JQM7; -.
DR STRING; 188379.A0A091JQM7; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543:SF132; BETA,BETA-CAROTENE 15,15'-DIOXYGENASE; 1.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Monooxygenase {ECO:0000313|EMBL:KFP22892.1};
KW Oxidoreductase {ECO:0000313|EMBL:KFP22892.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119}.
FT BINDING 151
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 215
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 286
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 491
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP22892.1"
FT NON_TER 505
FT /evidence="ECO:0000313|EMBL:KFP22892.1"
SQ SEQUENCE 505 AA; 57842 MW; 3AF96CD4A63E1A2C CRC64;
GQLPTWLQGI LLRNGPGMHT VGDTKYNHWF DGLALLHSFT FKNGEVYYRS KYLRSDTYNC
NVEANRIVVS EFGTMAYPDP CKNIFAKAVS YLSHTIPEFT DNCLINIMKT GDDFYATSET
NFIRKINPQT LETLDKVDYS KYVAVNVTTS HPHYDSAGNV LNMGTSIADK GKTKYVLFKI
PPSVPEKETK KSCFKYLEVV CSIPSRSLLH PSYYHSFGIT ENYIVFVEQP FKLDIVKMAT
AYIRGVNWAS CLAYHKEDKT WFHFVDKKTK KEVSTKFYTD SMVLFHHVNA YEEDGHIIFD
IIAYADNSLY DMFYLKNLNK VFEESEKLTS MPTCKRYVVP LQYDKDAEVG SNLVRLPSTA
TAIKEKDGSI YCQPEILCEG IELPRINYDY NGKEYKYIFA TEVQGTPVPT KVVKFNIQTK
EMLHWGEDHC WPSEPIFVPS PDAREEDDGI VLTCVVMSDP TKAPFLLVLD AKTFKELGRA
IVDVEMHLDL HGIFIPEKDL KTETE
//
