ID A0A091JTE6_EGRGA Unreviewed; 1078 AA.
AC A0A091JTE6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Leukemia inhibitory factor receptor {ECO:0000313|EMBL:KFP23045.1};
DE Flags: Fragment;
GN ORFNames=Z169_13319 {ECO:0000313|EMBL:KFP23045.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP23045.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP23045.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP23045.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00008921}.
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DR EMBL; KK502394; KFP23045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091JTE6; -.
DR STRING; 188379.A0A091JTE6; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003529; Hematopoietin_rcpt_Gp130_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR048497; LIF-R-like_Ig-like.
DR InterPro; IPR040817; LIFR_D2.
DR InterPro; IPR040901; LIFR_N.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF105; LEUKEMIA INHIBITORY FACTOR RECEPTOR; 1.
DR Pfam; PF21177; LIF-R_Ig-like; 1.
DR Pfam; PF17971; LIFR_D2; 1.
DR Pfam; PF18207; LIFR_N; 1.
DR SMART; SM00060; FN3; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS01353; HEMATOPO_REC_L_F2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KFP23045.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 810..835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 410..509
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 514..605
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 700..809
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 902..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 994..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1078
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP23045.1"
FT NON_TER 1078
FT /evidence="ECO:0000313|EMBL:KFP23045.1"
SQ SEQUENCE 1078 AA; 120092 MW; 632B82B5214405F5 CRC64;
ILCLRSLIYS QEIGSLGHPQ NLKCVTHNLR KMICTWDVSS KARHGQTDFC YTTNDLPPPV
CFKTKEKRVE ILIPESSTTV TITTNSVSGT AFATKEFEIH KKDISFVPLT PHILSLTPDF
STSTLNLKWS DNGSVFPYGL DAFWQIQILR KEAMEKVTQV TYHSKLTHED IVLSWNWTSD
MPLECTSHYV KIRCYINVTQ FGGPKDWSDW SPVEEVPGKD TEPNGNGVFP QDTVVAVGSD
VTICCVHKEG QQIQRMTYGP EIYPMVHLSS RSSAIRVLNA SASDTSGTNV VCILSEDEMD
GTVLFVGYAP DIPQDLSCET SNFLIIKCTW KPGRPSGLYG KRRTKYSLFE RISGKNVSCE
VNEMNRERVC GFPVLADQKT YDFILGVSNP IGQTESSLLV DLTQRVHPKN PEKLTVSGNS
STSVHLRWFI NGSFAETRLL CQIEISNGHS ERKLHNVSMP GGKFSTYAAQ LNALHPYTKY
QFRVRCSAAD HFWRWSGWSR AEEHTTLEAP PAKGPDIWRE RSPSGKSLKI FWKPLSLSEA
NGKIVSHEVS CYLPETPLEY KEVTEPSNST EIKLGKKDCV ISVVAKNHAG SSPPSRITSV
ELPSDNVKTD RAVAMGNGIY ISWSSYPNMT CGYIVKWCHS SGSEPCSVDW QKFPSNTTDA
VIKSGLFRPG VRYNFSLYGC KSSGYQLLKN ITGYMKELPP KRAPNFTVEE TSSDSILVKW
EDIPIEDCQG FLEGYRLSFA KGEKDALKPR LSESGNPELK VKNITDLTKK SLKILDLQGK
TSYQLDLQAY TAGGLSPPNS LYVVTKEDSV GLIIAILIPV AVVVLLGVVA SIFCYRKREW
IKETFYPEIP NPENSKALQF QKNICEGNKT LKTLEMNPCT PNSVEVVETR SAAPKIEDTE
IKSPAADTTV PEDGSDSETE NHVVVSYCPP IIEEEISNPP MDEPVGSSQV VYIDIQSMYQ
PQIKPEEEPE IDLVTTAGYK PQMQLPISAL KIESRSPAEE ELDKTAGYRP QANTNAWNMD
TPDSPGSVES NNENASFGSP CSINSRQFLL PPKDDEDSPK PSNVGWSFTH FFQNKPND
//
