ID A0A091JW08_EGRGA Unreviewed; 671 AA.
AC A0A091JW08;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Iron-sulfur clusters transporter ABCB7, mitochondrial {ECO:0000256|ARBA:ARBA00041016};
DE AltName: Full=ATP-binding cassette sub-family B member 7, mitochondrial {ECO:0000256|ARBA:ARBA00042945};
DE Flags: Fragment;
GN ORFNames=Z169_13398 {ECO:0000313|EMBL:KFP15751.1};
OS Egretta garzetta (Little egret).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta.
OX NCBI_TaxID=188379 {ECO:0000313|EMBL:KFP15751.1, ECO:0000313|Proteomes:UP000053119};
RN [1] {ECO:0000313|EMBL:KFP15751.1, ECO:0000313|Proteomes:UP000053119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Z169 {ECO:0000313|EMBL:KFP15751.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(glutathione)4[2Fe(III)-2S] cluster(in) + ATP + H2O =
CC (glutathione)4[2Fe(III)-2S] cluster(out) + ADP + H(+) + phosphate;
CC Xref=Rhea:RHEA:67028, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:167627,
CC ChEBI:CHEBI:456216; Evidence={ECO:0000256|ARBA:ARBA00036789};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67029;
CC Evidence={ECO:0000256|ARBA:ARBA00036789};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK501542; KFP15751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091JW08; -.
DR STRING; 188379.A0A091JW08; -.
DR Proteomes; UP000053119; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18582; ABC_6TM_ATM1_ABCB7; 1.
DR CDD; cd03253; ABCC_ATM1_transporter; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF402; IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053119};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..354
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 390..624
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP15751.1"
FT NON_TER 671
FT /evidence="ECO:0000313|EMBL:KFP15751.1"
SQ SEQUENCE 671 AA; 74014 MW; 9041D4EF85888222 CRC64;
ILPSWRLIEK RMCWHGHAGG GLHTDPKEGL KEIDAKKIIR AMLSYVWPKD RPDLRARVAI
SLGFLASAKA MNILVPFMFK YAVDNLNQVS GNILNLSDTP NTVATVATAV LIGYGISRAG
AALFNEARNA VFGKVAQNSI RRIAKNVFLH LHNLDLAFHL SRQTGALSKT IDRGTRGISF
VLSALVFNLG PTMFEVALVS GILYYKCGAE FALVTLGTLG AYAAFTIGIT QWRTKFRIEM
NKADNDAGNA AIDSLLNYET VKYFNNEKYE AQRYDEFLKT YENASLKTTS TLALLNFGQS
AIFSIGLTAI MVLASQGIVA GSLSVGDLVM VNGLLFQLSL PLNFLGTVYR ETRQALIDMN
TLFTLLSVDT KIKDKELAPP LQITPQTAAI AFDNVHFEYL EGQKVLAGVS FEVPAGKKVA
IVGGSGSGKS TIVRLLFRFY EPQKGNIYIA GQNIQDVSLE SLRKAIGVVP QDAVLFHNTI
YYNLLYGNID ATPEEVYAVA KLAGIHDAIL RMPNGYNTQV GERGLKLSGG EKQRVAIARA
MLKEPLIFLY DEATSSLDSI TEENILSAMR DMVKHRTSVF IAHRLSTVVD ADEIIVLDQG
KVVERGRHAD LLASPSNLYY EMWHTQSSKV LNSHNNSDWE ERNHRVSKEE ERKKLEEEII
NSVKGCGNCS C
//
