ID A0A091JW50_COLST Unreviewed; 662 AA.
AC A0A091JW50;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Leucine-rich repeat transmembrane protein FLRT2 {ECO:0000313|EMBL:KFP29402.1};
GN ORFNames=N325_08307 {ECO:0000313|EMBL:KFP29402.1};
OS Colius striatus (Speckled mousebird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coliiformes; Coliidae; Colius.
OX NCBI_TaxID=57412 {ECO:0000313|EMBL:KFP29402.1, ECO:0000313|Proteomes:UP000053615};
RN [1] {ECO:0000313|EMBL:KFP29402.1, ECO:0000313|Proteomes:UP000053615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N325 {ECO:0000313|EMBL:KFP29402.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004162}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK536020; KFP29402.1; -; Genomic_DNA.
DR RefSeq; XP_010194473.1; XM_010196171.1.
DR AlphaFoldDB; A0A091JW50; -.
DR GeneID; 104553485; -.
DR KEGG; csti:104553485; -.
DR CTD; 23768; -.
DR OrthoDB; 2916435at2759; -.
DR Proteomes; UP000053615; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF16; LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01463; LRRCT; 1.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053615};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:KFP29402.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..35
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 36..662
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001875679"
FT TRANSMEM 543..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 420..519
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 662 AA; 74725 MW; EB468A2A375C236E CRC64;
MGLWTRMWPT DWAILMKSWF IFSLGLYMQV SKTLACPKVC RCDRNFVYCN ERSLTSVPLG
IPEGVTVLYL HNNQINNAGF PAELHNVQSV HTVYLYGNQL DEFPMNLPKN VRVLHLQENN
IQTISRAALA QLLKLEELHL DDNSISTVGV EDGAFREAIS LKLLFLSKNH LSSVPVGLPV
DLQELRVDEN RIAVISDLAF QNLTSLERLI VDGNLLTNKG IAEGTFSHLT KLKEFSIVRN
SLTYPPPDLP GTHLLRLYLQ DNQITHIPLT AFSNLLKLER LDISNNQLRM LVKGVFDNLR
NLRQLTVRNN PWLCDCSIKW VTEWLKYIPA SINVRGFMCQ GPEQVRGMAV RELNMNLLSC
PTTTPGLPLI ITPVPATAMP TTLVPTSSVP PTSSKYNPLT PNIVTLPTVP EREDRERTMP
PISERIQLSI HFVNDTCIQV NWMSLFTVMA YKLTWVKMGH SLVGGIVQER IVSGEKQHLS
LVNLEPKSTY RICLVPLDAY NNYRTGEDTV CSEATTKASF LSNGSNIPSS HEQTTSQNLG
SPFLLAGLIG GAVIFVLVVL LSIFCWHMHK KGRYTSQKWK YNRGRRKDDY CEAGTKKDNS
ILEMTETSFQ IVSLNNDQLL KGDFRLQPIY TPNGGINYTD CHIPNNMRYC NSNVSDLEHC
HT
//
