ID A0A091K0Q5_COLST Unreviewed; 1321 AA.
AC A0A091K0Q5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Pleckstrin homology domain-containing family H member 1 {ECO:0000313|EMBL:KFP29931.1};
DE Flags: Fragment;
GN ORFNames=N325_04229 {ECO:0000313|EMBL:KFP29931.1};
OS Colius striatus (Speckled mousebird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coliiformes; Coliidae; Colius.
OX NCBI_TaxID=57412 {ECO:0000313|EMBL:KFP29931.1, ECO:0000313|Proteomes:UP000053615};
RN [1] {ECO:0000313|EMBL:KFP29931.1, ECO:0000313|Proteomes:UP000053615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N325 {ECO:0000313|EMBL:KFP29931.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK537816; KFP29931.1; -; Genomic_DNA.
DR Proteomes; UP000053615; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13206; FERM_C-lobe_PLEKHH1_PLEKHH2; 1.
DR CDD; cd00821; PH; 1.
DR CDD; cd13282; PH1_PLEKHH1_PLEKHH2; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22903:SF4; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 1; 1.
DR PANTHER; PTHR22903; PLEKHH PROTEIN; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053615};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 531..625
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 640..748
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 784..938
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 949..1282
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 338..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 442..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2..78
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 452..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP29931.1"
FT NON_TER 1321
FT /evidence="ECO:0000313|EMBL:KFP29931.1"
SQ SEQUENCE 1321 AA; 148470 MW; 8CBADD73F718C008 CRC64;
KMQELEQRVI EAEQRAEDAE KQVRVMEEKI KLANMKTIEA DSTLHRKYQE LMGTVQGKED
LINRLETQLT KQKQLRTEEA KIVQEKAAKI KEWVTFKLRE LELENYHLKK CNERLTEHIE
ALQDTLQGKC VHLALQPRNH HMSGSQLSGV LFLTFGSIFK TEIHCLPDLK TLLLVSHHAV
TTLQQVALHS TRFSDDLSAR FRSHQLGSSS SGEILSMLKG QLQTGEPPLV VSTATVTAHP
FGAGRECGLG SNMTFPKIRT PNTPRDSIQL AKRHYSQPQP GANSFHRVMS LEASTFQPIT
DSSVCHGQVK ETDIDDDDEV LEKMETERGP VREEAGVYEE PGGFSAGQRE GVTSEAGVPD
PGGKPPTPPL HRFPSWESRI YAVAKSGMRL SEVAMVNDTS SCFSNFSCST SGPFTRLIYR
NVTVPVYTTL KGRATQISNV PFLDESSGSD DDCGSHASFR TSTAGSEHRK ASVPGSPRAV
KRGVSMSSLS SESDYAIPPD AYSLDGDSSE PEHKLQRTSS YSTDGGICTE PMEKSGYLLK
MSSQVKMWKR RWFVLRNRQI MYYKSPSDVI RKPQGQMELN SSCQIVRGEG SQTFQLMTEK
RTYFLTADSP SILEEWIHVL QSILRVQVTG PVGVPHNDAK PTVKGWLTKV KHGHSKLVWC
TLIGKTFYYY RNHEDKCPLG HLPMRESKVE EVDRSCDSDE DYEATGGGLL SSHCTLVIHP
QDQSPTYLLI RTKQEKNTWL YHLTVAAGSS SAIVGTSYEQ LIGKLLDAEG DPDSPLWKHP
MLCYSKDGLH TSLTTLPSEA LQTEALKLFK SCQLFINVPV EAPSIDYHVS LAQTALQVCL
THTELQNEIY CQLVKQTSCR QPQNHSVIQC WQLMALCAPL FLPQHHFLWY IKQHLQRHAD
PRSEIGKYAI YCQRSVDRTV HAGEREAKPS RMEIVSILLR NPYHHSLPFS IPVHFMNGTY
QVVGFDGSST VDEFIQTLNQ ETGMRKPSHM GFSLFTDDPS GRNLEHCLQD SMKICDVISK
WEQALKELHP GKYEGGTRTV KLTYKNRLYF RSQAKGETDR ERLLLAFQVS NEIANGRFPV
NKELALEMVA LMAQVEYGDL DRPGSSSPGG TSQSKMQHLL HQVLDKFYPK RYKQNITPEQ
LRQLADRLAT KWMVLQGCSP PECVRIYLTV ARKWPLFGTK IFAAKPILPS SLEDCPVWIA
VNEDGISILD YNTMHLKVSY SYSSVLTFGG CRDDFMIVVS QIKERTSGKN STEKLLFTMA
IPKIVEATLL IASYINYRST PSLLSPAQPS RSKTPANKLW ESESQCFFPS VPRSTKGPTL
L
//
