ID   A0A091K4H8_COLST        Unreviewed;       857 AA.
AC   A0A091K4H8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=SLIT and NTRK-like 2 {ECO:0000313|EMBL:KFP31028.1};
GN   ORFNames=N325_10589 {ECO:0000313|EMBL:KFP31028.1};
OS   Colius striatus (Speckled mousebird).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coliiformes; Coliidae; Colius.
OX   NCBI_TaxID=57412 {ECO:0000313|EMBL:KFP31028.1, ECO:0000313|Proteomes:UP000053615};
RN   [1] {ECO:0000313|EMBL:KFP31028.1, ECO:0000313|Proteomes:UP000053615}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N325 {ECO:0000313|EMBL:KFP31028.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the SLITRK family.
CC       {ECO:0000256|ARBA:ARBA00010439}.
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DR   EMBL; KK541579; KFP31028.1; -; Genomic_DNA.
DR   RefSeq; XP_010198545.1; XM_010200243.1.
DR   AlphaFoldDB; A0A091K4H8; -.
DR   GeneID; 104556396; -.
DR   KEGG; csti:104556396; -.
DR   CTD; 84631; -.
DR   OrthoDB; 4629004at2759; -.
DR   Proteomes; UP000053615; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007409; P:axonogenesis; IEA:InterPro.
DR   GO; GO:1905606; P:regulation of presynapse assembly; IEA:InterPro.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR000483; Cys-rich_flank_reg_C.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR043326; Slitrk.
DR   PANTHER; PTHR45773:SF4; SLIT AND NTRK-LIKE PROTEIN 2; 1.
DR   PANTHER; PTHR45773; SLIT AND NTRK-LIKE PROTEIN 4-RELATED; 1.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00369; LRR_TYP; 10.
DR   SMART; SM00082; LRRCT; 2.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS51450; LRR; 2.
PE   3: Inferred from homology;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053615};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..857
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001877291"
FT   TRANSMEM        630..656
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          217..265
FT                   /note="LRRCT"
FT                   /evidence="ECO:0000259|SMART:SM00082"
FT   DOMAIN          533..591
FT                   /note="LRRCT"
FT                   /evidence="ECO:0000259|SMART:SM00082"
FT   REGION          262..322
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..283
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..301
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   857 AA;  96717 MW;  5327D37CFB43FBFB CRC64;
     MLKGVWLLSL LTVAGISQTE SRKPAKDICS KSRCPCEEKE NVLNINCENK GFTTVSLLLP
     PPSKIYQLFL NGNALTRLFP NEFVNYSNAV TLHLGNNDMQ EIRTGAFSGL RTLKRLHLNN
     NKLEVLKEDT FLGLESLEYL QADYNYISAI EAGAFSKLNK LKVLILNDNL LLSLPSNVFR
     FVLLTHLDLR GNRLKMMPFA GVLEHIGGIM EIQLEENPWN CTCDLLPLKA WLDTITVFVG
     EIVCETPFRL HGKDVTQLTR QDLCPRKSSS DSNQREKHPV LSDPHVSRLS PTANSAINPT
     RAPKASRPPK TRNRPTPRVT VSKDRQIFGP IMVYQTKSPV PITCPAGCIC TSQSSDNGLN
     VNCQEKKISN ISDLHPKPTS PKKLYLTSNY LQVIYRTDLT EYSSLDLLHL GNNRIAVIQE
     GAFTNLTSLR RLYLNGNYLE ILYPSMFKGL HSLQYLYLEY NVIKEILPRT FDALSNLHLL
     FLNNNLLRSL PDNVFSGTSL TRLNLRNNHF SHLPVRGVLD QLSALIQIDL QENPWDCTCD
     ILGLRNWIEK VTDQNNQQSN PPVVINEVIC ESPTKHSGEH LKFLSKEAIC PENPNLSDSS
     LPSVNQNTDT PHLLGVSPSS YPEIHTEVPL SVLILGLLVV FILSVCFGAG LFVFVLKRRK
     GVQSMPSSAN NLDISSFQLQ YGSYNTESHD KTEGHVYNYI PPPVGQMCQN PIYMQKEGDP
     VAYYRNLHEF SYSSLDHKKE DPTSLAFTIS AADLLEKQSS PREPELLYQN IAERVKELPA
     GGLVHYNFCT LPKRQFAPSY ESRRQNQDRI NKTVLYGTPR KYFAEQSKPE HPLLQGKLQT
     EPDYLEVLEK QTAISQL
//