ID A0A091K9G3_COLST Unreviewed; 1925 AA.
AC A0A091K9G3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Myosin-6 {ECO:0000313|EMBL:KFP32833.1};
DE Flags: Fragment;
GN ORFNames=N325_09439 {ECO:0000313|EMBL:KFP32833.1};
OS Colius striatus (Speckled mousebird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coliiformes; Coliidae; Colius.
OX NCBI_TaxID=57412 {ECO:0000313|EMBL:KFP32833.1, ECO:0000313|Proteomes:UP000053615};
RN [1] {ECO:0000313|EMBL:KFP32833.1, ECO:0000313|Proteomes:UP000053615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N325 {ECO:0000313|EMBL:KFP32833.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Muscle contraction. {ECO:0000256|ARBA:ARBA00037488}.
CC -!- SUBUNIT: Muscle myosin is a hexameric protein that consists of 2 heavy
CC chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2
CC regulatory light chain subunits (MLC-2).
CC {ECO:0000256|ARBA:ARBA00038612}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KK547699; KFP32833.1; -; Genomic_DNA.
DR Proteomes; UP000053615; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF11; MYOSIN-6; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000053615}.
FT DOMAIN 30..79
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 83..772
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 649..671
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1906..1925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 834..1150
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1925
FT /evidence="ECO:0000313|EMBL:KFP32833.1"
SQ SEQUENCE 1925 AA; 222124 MW; 429A6BF544079949 CRC64;
MMDMSEFGEA APFLRKSEKE LMMAQTVAFD GKKKCWVPDD KKAYVEAEIT ETSGGKVTVQ
TTDGRTMTIK EDDVQSMNPP KFDMIEDMAM LTHLNEASVL YNLRKRYSNW MIYTYSGLFC
VTINPYKWLP VYKSEVVAAY KGKRRSEAPP HIFSIADNAY HDMLRNRENQ SMLITGESGA
GKTVNTKRVI QYFATVAALG EPGKKSGTLE DQIIQANPAL EAFGNAKTLR NDNSSRFGKF
IRIHFGTTGK LSSADIEIYL LEKSRVIFQQ PGERDYHIFY QILSGKKPEL LDMLLVSTNP
YDYHFCSQGV VTVDNLDDGE ELLATDQAMD ILGFVPDEKS GSYKLTGAIM HFGNMKFKQR
PREEQAEADG TESADKAAYL MGINSSDLIK GLLHPRVKVG NEYVTKGQSV EQVLYAVGAL
SKAVYDRMFK WLVVRINKTL DTKLPRQFFI GVLDIAGFEI FDFNSFEQLC INYTNEKLQQ
FFNHHMFVLE QEEYKKEGID WVFIDFGMDL QACIDLIEKP LGILSILEEE CMFPKATDMT
FKAKLYDNHL GKSPNLQKPR PDKKRKYEAH FELLHYAGAV PYNIIGWLEK NKDPLNETVV
GIFQKSSNKL LASLFESYIG ADSADQGGEK KRKKGASFQT VSSLHKENLN KLMTNLKSTA
PHFVRCIIPN ESKTPGEMDA FLVLHQLRCN GVLEGIRICR KGFPNRVLYA DFKQRYRILN
PGAIPEDKFV DSRKAAEKLL ASLDVDHNQY RFGHTKVFFK AGLLGHLEEM RDERLAKILT
MIQARARGRL MRIEFQKIVE RRDALLVIQW NIRAFMAVKN WPWMKLFFKI KPLLKSAETE
KEMANMKEEF LKLKEALEKS ETRRKELEEK QVSLVQEKND LLLQLQAEQD TLADAEERCD
LLIKSKIQLE AKVKELTERV EDEEEMNSEL TSKKRKLEDE CSELKKDIDD LEITLAKVEK
EKHATENKVK NLTEEMATLD ENISKLTKEK KSLQEAHQQV LDDLQAEEDK VNTLSKAKVK
LEQQVDDLEG SLEQEKKVRM DLERAKRKLE GDLKLTQESV MDLENDKLQM EEKLKKKEFE
MSQLNSKIED EQAIVMQLQK KIKELQARIE ELEEELEAER AARAKVEKQR SDLARELEEL
SERLEEAGGA TAAQLEMNKK REAEFLKLRR DLEEATLHYE ATAATLRKKH ADSVAEMGEQ
LDNLQRVKQK LEKEKSELKM EVDDLSSNME QMVKGKANAE KLCRTYEDHL NETKTKLEEM
TRLMNDLTTQ KAKLQSENGE FTRQLEEKES LISQLSRGKT SFTQQIEELR RQLEEETKSK
NALAHALQAA RHDCDLLREQ YEEEQEAKAE LQRALSKGNA EVAQWRTKYE TDAIQRTEEL
EDAKKKLAAR LQEAEEAIEA ANAKCSSLEK TKHRLQNELE DMMIDLEKAN SAAASLDKKQ
RGFDKIINDW KQKYEESQAE LEAAQKEARG LSTELFKLKN AYEETLDHLE TLKRENKNLQ
EEISDLTNQI SEGNKTLHEI EKVKKQVEQE KSEVQLALEE AEGALEHEES KTLRFQLELS
QLKAEFERKL AEKDEEMENI RRNQQRAIDS LQSTLDSEAR SRNEAIRLKK KMEGDLNEME
IQLSHANRHA AEATKSARVL QTQIKEIQVQ LDDSGHVNED LKEQLAVSDR RNNLLQSELD
ELRALLDQTE RARKLAEHEL LEATERVNLL HTQNTSLINQ KKKLEGDISQ MQNEVEESMQ
ECRNAEEKAK KAITDAAMMA EELKKEQDTS AHLERMKKNM EQTIKDLQKR LDEAEQIALK
GGKKQIQKLE SRVRELENEL ETELRRNSDA QKGARKFERR IKELTYQSEE DKKNLARMQD
LIDKLQLKVK SYKHQAEEAE AQANLYLSKY RKQQHDLDDA EERAEIAESQ VNKLRSKSRD
IGMKK
//
