ID A0A091KMG3_9GRUI Unreviewed; 731 AA.
AC A0A091KMG3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=SLIT-ROBO Rho GTPase-activating protein 2 {ECO:0000313|EMBL:KFP40673.1};
DE Flags: Fragment;
GN ORFNames=N324_11531 {ECO:0000313|EMBL:KFP40673.1};
OS Chlamydotis macqueenii (Macqueen's bustard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP40673.1, ECO:0000313|Proteomes:UP000053330};
RN [1] {ECO:0000313|EMBL:KFP40673.1, ECO:0000313|Proteomes:UP000053330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP40673.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK747421; KFP40673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091KMG3; -.
DR Proteomes; UP000053330; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04383; RhoGAP_srGAP; 1.
DR CDD; cd11955; SH3_srGAP1-3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035648; srGAP1/2/3_SH3.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14166:SF6; SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..238
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 436..624
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 673..731
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 95..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 276..310
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 95..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP40673.1"
FT NON_TER 731
FT /evidence="ECO:0000313|EMBL:KFP40673.1"
SQ SEQUENCE 731 AA; 83960 MW; C393C1F9F620E190 CRC64;
RKDQNVLSPV NCWNLLLNQV KRESRDHTTL SDIYLNNIIP RFVQVSEDSG RLFKKSKEVG
LQLQEDLMKV LNELYTVMKT YHMYNADSIS AQSKLKEAEK QEEKQIGKSV KQEDKQTPRS
PDSTSNIKFE EKHVRRSSVK KIEKMKEKRQ AKYTENRLKA IKARNEYLLA LEATNASVFK
YYIHDLSDLI DCCDLGYHAS LNRALRTFLS AELNLEQSKH EGLDAIENAV ENLDANSDKQ
RLMEMYNNVF CPPMKFEFQP HMGDMESQLC AQQPVQSELV QRCQQLQSRL STLKIENEEV
KKTMEATLQT IQDIVTIEDF DVSDCFQYSN SMESVKSTVS ETFMSKPSIA KRRANQQETE
QFYFTKMKEY LEGRNLITKL QAKHDLLQKT LGESQRTDCS LARNQRAPSC FPPPQSGSAR
KQLLRFIPNF VFSKEPYVTD FHVDSSQAIP LVVESCIRFI SRHGLQHEGI FRVSGSQVEV
NDIKNAFERG EDPLAGDQND HDMDSIAGVL KLYFRGLEHP LFPKDIFHDL IACVTMDNLQ
ERALHIRKVL LNLPKTTLIV MRYLFAFLNH LSQFSEENMM DPYNLAICFG PTLMSVPEGH
DQVSCQAHVN ELIKTIIIQH ENIFPGPREL EGPVYSRGGN TEDYCESPHG ERASTEDSAQ
DVTAEHHTSD DECEPIEAIA KFDYIGRTAR ELSFKKGASL LLYQRASDDW WEGRHNGIDG
LIPHQYIVVQ D
//
