ID A0A091KT42_COLST Unreviewed; 521 AA.
AC A0A091KT42;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000256|ARBA:ARBA00044114};
GN ORFNames=N325_04392 {ECO:0000313|EMBL:KFP30934.1};
OS Colius striatus (Speckled mousebird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coliiformes; Coliidae; Colius.
OX NCBI_TaxID=57412 {ECO:0000313|EMBL:KFP30934.1, ECO:0000313|Proteomes:UP000053615};
RN [1] {ECO:0000313|EMBL:KFP30934.1, ECO:0000313|Proteomes:UP000053615}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N325 {ECO:0000313|EMBL:KFP30934.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Exhibits strong synaptogenic activity, restricted to
CC excitatory presynaptic differentiation, acting at both pre- and
CC postsynaptic level. {ECO:0000256|ARBA:ARBA00043936}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00035006}; Single-pass
CC type I membrane protein {ECO:0000256|ARBA:ARBA00035006}.
CC -!- SIMILARITY: Belongs to the LRRTM family.
CC {ECO:0000256|ARBA:ARBA00038250}.
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DR EMBL; KK541155; KFP30934.1; -; Genomic_DNA.
DR RefSeq; XP_010198251.1; XM_010199949.1.
DR AlphaFoldDB; A0A091KT42; -.
DR GeneID; 104556193; -.
DR KEGG; csti:104556193; -.
DR CTD; 347730; -.
DR OrthoDB; 5344967at2759; -.
DR Proteomes; UP000053615; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24373:SF290; LEUCINE-RICH REPEAT TRANSMEMBRANE NEURONAL PROTEIN 1; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053615};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:KFP30934.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..521
FT /note="Leucine-rich repeat transmembrane neuronal protein
FT 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001877415"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..70
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
SQ SEQUENCE 521 AA; 59127 MW; 51DE92FB97938DFA CRC64;
MDFLLIGLCL NWLLRKPPGL ILCTLGIFSK MLPAVNSGCP QLCRCEGRLL YCESLNLTEM
PRNLSGMMGL SLRYNSLSEL HDGQFTGLMQ LTWLYLDHNH ICSVEGNAFQ KLRRLKELTL
SSNKITQLPN NTFRPMPNLR SVDLSYNNLQ SLEPDLFHGL RKLTTLHMRS NAIKFVPVRI
FQDCRSLKFL DIGYNQLKSL ARNSFAGLFK LTELHLEHND LVKVNLAHFP RLISLHSLCL
RRNKVTIVVN TLDWIWQLEK MDLSGNEIEY IEPHVFESVP HLKSLQLDSN RLTYIDSRVL
DSWKSLTSIS LSANAWDCSR NVCALASWLS NFKGRYDSNL LCATPDYAQG EDVLDAVYAF
HLCEDAADPT SVNTLSPVTN NSDQTFSYGL ATATYDVEDG DGDPTTYAIT VTMPGENSEN
AVQIHKVVTG TMALIFSFLI VVLVLYVSWK CFPAGLRQLR QCFVTQRRKQ KQKQTMHQMA
AMSAQEYYVD YKPNHIEGAL VIINEYGSCS CHQQPARECE V
//
