ID A0A091L0A5_9GRUI Unreviewed; 343 AA.
AC A0A091L0A5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Lumican {ECO:0000256|ARBA:ARBA00013370};
GN ORFNames=N324_00912 {ECO:0000313|EMBL:KFP45692.1};
OS Chlamydotis macqueenii (Macqueen's bustard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP45692.1, ECO:0000313|Proteomes:UP000053330};
RN [1] {ECO:0000313|EMBL:KFP45692.1, ECO:0000313|Proteomes:UP000053330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP45692.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Binds to laminin. {ECO:0000256|ARBA:ARBA00011719}.
CC -!- SIMILARITY: Belongs to the small leucine-rich proteoglycan (SLRP)
CC family. SLRP class II subfamily. {ECO:0000256|ARBA:ARBA00005818}.
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DR EMBL; KK763679; KFP45692.1; -; Genomic_DNA.
DR RefSeq; XP_010126524.1; XM_010128222.1.
DR AlphaFoldDB; A0A091L0A5; -.
DR GeneID; 104485768; -.
DR KEGG; cmac:104485768; -.
DR CTD; 4060; -.
DR OrthoDB; 521898at2759; -.
DR Proteomes; UP000053330; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF6; LUMICAN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01462; LRRNT; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00022974};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Proteoglycan {ECO:0000256|ARBA:ARBA00022974};
KW Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Sulfation {ECO:0000256|ARBA:ARBA00022641}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..343
FT /note="Lumican"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001876060"
FT DOMAIN 39..73
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
SQ SEQUENCE 343 AA; 38668 MW; 819BC31236B40970 CRC64;
MTLNSLPIFL LLISGIFCQY DYGPADDYGY DPFGPSSAVC APECNCPLSY PTAMYCDNLK
LKTIPIVPSG IKYLYLRNNM IEGIEENTFD NVTDLQWLIL DHNHLENSKI KGRVFSKLKH
LKKLHINYNN LTEAVGPLPK TLDDLQLSHN KITKVNPSAL EGLVNLTVIH LQNNQLKAES
ISGAFKGLNS LLYLDLSFNR LTKLPSGLPH SLLMLYFDNN QISNVPDEYF QGFKALQYLR
LSHNKLTDSG IPGNVFNITS LVELDLSFNQ LKSIPTVSEN LENFYLQVNK INKFPLSSFC
KVVGPMTYSK ITHLRLDGNN LTRADLPQEM YNCLRVAAEI SLE
//
