ID A0A091L0M6_9GRUI Unreviewed; 562 AA.
AC A0A091L0M6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Neurogenic locus notch protein 2 {ECO:0000313|EMBL:KFP45253.1};
DE Flags: Fragment;
GN ORFNames=N324_11490 {ECO:0000313|EMBL:KFP45253.1};
OS Chlamydotis macqueenii (Macqueen's bustard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP45253.1, ECO:0000313|Proteomes:UP000053330};
RN [1] {ECO:0000313|EMBL:KFP45253.1, ECO:0000313|Proteomes:UP000053330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP45253.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KK762114; KFP45253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091L0M6; -.
DR Proteomes; UP000053330; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 11.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24044:SF496; METALLOENDOPEPTIDASE; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF00008; EGF; 12.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF12661; hEGF; 2.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00181; EGF; 14.
DR SMART; SM00179; EGF_CA; 15.
DR SUPFAM; SSF57196; EGF/Laminin; 8.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 11.
DR PROSITE; PS00022; EGF_1; 13.
DR PROSITE; PS01186; EGF_2; 13.
DR PROSITE; PS50026; EGF_3; 15.
DR PROSITE; PS01187; EGF_CA; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Notch signaling pathway {ECO:0000256|ARBA:ARBA00022976};
KW Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 4..40
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 42..78
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 80..116
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 118..153
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 155..194
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 196..232
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 234..272
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 274..310
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 312..348
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 350..386
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 388..424
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 426..462
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 463..498
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 500..536
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 538..562
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 30..39
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 68..77
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 106..115
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 122..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 143..152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 222..231
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 243..260
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 262..271
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 300..309
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 338..347
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 376..385
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 414..423
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 452..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 488..497
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 526..535
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP45253.1"
FT NON_TER 562
FT /evidence="ECO:0000313|EMBL:KFP45253.1"
SQ SEQUENCE 562 AA; 60508 MW; B8CCDDF673805792 CRC64;
CEMDINECHS NPCQNDATCL DKIGGFTCLC MPGFKGVHCE EDIDECLSNP CVNNGECLDK
VNRFLCVCPP GFSGAVCQID IDDCSSTPCL NGAKCIDHPN GYECQCATGF TGLLCEENIN
NCDPDPCHHG ECQDGIDSYT CICNPGYMGA ICSEQIDECH SNPCLHQGRC IDLVNGYQCN
CLLGTSGWIG DYCATEGNEC KSNPCQNGGT CEDLLNGYRC TCRKGFKGVN CQVVVAPCSP
DPCENSGICQ ESPDSEGYTC QCAPGWEGER CTVDIDECLS KPCKNHALCH NIQGSYLCEC
RPGFTGGDCD SNIDDCLSNP CQNGASCVDG INSFSCICLP GFHGDKCQTD TNECLSEPCR
NGGTCTHYVN SYTCKCQPGF EGTNCENNID ECTESSCFNG GTCVDGINSF TCQCPVGFTG
PFCLMEINEC DSHPCLNKGS CVDSLGTYRC ICPLGYTGRN CQVGVTVDQL CQHSGHCFNV
GNTHHCRCQV GYTGSYCEVQ LNECDSSPCQ NGATCRDHLG GYQCECVPGY QGVNCEYEVD
ECQFQPCQNG GTCIDLVNHF KC
//
