ID A0A091L601_CATAU Unreviewed; 1186 AA.
AC A0A091L601;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Nidogen-1 {ECO:0000313|EMBL:KFP50678.1};
DE Flags: Fragment;
GN ORFNames=N323_06080 {ECO:0000313|EMBL:KFP50678.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP50678.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP50678.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP50678.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted, extracellular space, extracellular matrix, basement membrane
CC {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL297617; KFP50678.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091L601; -.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00053; EGF; 1.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00255; nidG2; 1.
DR CDD; cd00191; TY; 1.
DR Gene3D; 2.40.155.10; Green fluorescent protein; 1.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR Gene3D; 4.10.800.10; Thyroglobulin type-1; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR006605; G2_nidogen/fibulin_G2F.
DR InterPro; IPR009017; GFP.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR000716; Thyroglobulin_1.
DR InterPro; IPR036857; Thyroglobulin_1_sf.
DR PANTHER; PTHR46513:SF6; NIDOGEN-1; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF12947; EGF_3; 2.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF07474; G2F; 1.
DR Pfam; PF00058; Ldl_recept_b; 3.
DR Pfam; PF06119; NIDO; 1.
DR Pfam; PF00086; Thyroglobulin_1; 1.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00682; G2F; 1.
DR SMART; SM00135; LY; 5.
DR SMART; SM00539; NIDO; 1.
DR SMART; SM00211; TY; 1.
DR SUPFAM; SSF54511; GFP-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR SUPFAM; SSF57610; Thyroglobulin type-1 domain; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS51120; LDLRB; 3.
DR PROSITE; PS51220; NIDO; 1.
DR PROSITE; PS50993; NIDOGEN_G2; 1.
DR PROSITE; PS00484; THYROGLOBULIN_1_1; 1.
DR PROSITE; PS51162; THYROGLOBULIN_1_2; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00500};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022869};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 31..194
FT /note="NIDO"
FT /evidence="ECO:0000259|PROSITE:PS51220"
FT DOMAIN 371..608
FT /note="Nidogen G2 beta-barrel"
FT /evidence="ECO:0000259|PROSITE:PS50993"
FT DOMAIN 609..650
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 651..693
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 698..741
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 742..780
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 786..858
FT /note="Thyroglobulin type-1"
FT /evidence="ECO:0000259|PROSITE:PS51162"
FT REPEAT 929..971
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 972..1014
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1015..1059
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DISULFID 828..835
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00500"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP50678.1"
FT NON_TER 1186
FT /evidence="ECO:0000313|EMBL:KFP50678.1"
SQ SEQUENCE 1186 AA; 130799 MW; D966564B2E927F10 CRC64;
VATNGIIAVN EPSSEEKYLG QFPVSFGAIA PFMADLDTTD GRGNVYYRED SSSDVLQLAS
DYIKRGFPET TFDPSSVVIV TWKLVAPYQA RGEDHTLEEK RNTFQAVLAS SDASSYAIFL
YPEDSLQFYS TYSKNDDGKI PAMVGFSQAS TNYYFWEKPG SYNIIANDED SIRNLHKSSN
AGKQGVWVFE IGSSSESIVP AKISDVLENL ESNEQDQEMT SKPFMSDYGS TEIRQQYVTS
SIDSTEEDQH HVTYSVPQLA AEDFLTSYQV VTGTPLTESF YSHQDFPTAK APPRQFQVQQ
FPPQQPQVID VEEFDETGIV FRYHTDVQQT CANNRHQCSV HAICKDYPNG FCCSCIAGYK
GNGRQCVAEG SPQRVNGKVK GRIFVGNNPV PVIFENTDLH SYVVMNQGRA YTAISTIPET
LGYSLLPLAS IGGIIGWMFA VEQQGYKNGF SVTGGEFTRQ TEVTFLGNNE KLVIKQKFSG
IDEHGHLTIS TEMEGRIPEI PSGASVHIEP YTELYHTSSS VITSSSTREY TVTEPERDGV
ASTYTGAYQW RQTISFDECI HDDSHHAASA TQQLSVDSVF VLYNRDEQIL RYAMSNSIGP
ISDGSADINR NPCYTGTHNC DTNAICRPGT GNRFFCECSI GFRGDGNVCY DVDECSEQPA
LCGSNAVCNN QPGTYLCECV EGYQFAADGQ TCVAVEYVVN HCQTGTHNCD IPQRAQCVYT
GGTAYICTCL PGFSGDGRAC EDVDECQQGH CHPDAFCYNT PGSFSCQCKA GYRGDGFRCV
LGEVEKTKCQ REREVALGSG GTFFPREIRD GHFIPQCDEH GNYLPTQCHS SSGYCWCVDR
DGNEIDGTRS GPGVRPPCLS TAAPPVVIGP SVRPDTVPLP PGTHLLFAQS GKIEHVPLDG
NSMKKNGAKA LLHIPDKVVI GVAYDCTDKM VYWTDISGPS ISRASLQGGE PTTIIKTDLG
SPEGIAVDHL GRNIFWTDSQ LDRIEVARLD GRQRRILFDT GLVNPRAIVV DPMRGNLYWT
DWNREAPKIE TSYMDGTNRR ILVKDDLGLP NGLTFDPYSS MLCWVDAGTK RVECMNPNQL
GRRKIVEGIQ YPFSVTSYGK NLYYTDWRRD AVVAVDRTIS IEKDNFQPHK RSRLYGITTA
FAQCPGGHNY CTVNNGGCTH LCLATPGGRS CRCPDNTVGV DCIERN
//
