ID A0A091LGA4_CATAU Unreviewed; 681 AA.
AC A0A091LGA4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
DE Flags: Fragment;
GN ORFNames=N323_10963 {ECO:0000313|EMBL:KFP55718.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP55718.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP55718.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP55718.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001031};
CC -!- PATHWAY: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-
CC glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-
CC fructose 6-phosphate: step 1/1. {ECO:0000256|ARBA:ARBA00004775}.
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DR EMBL; KL324259; KFP55718.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LGA4; -.
DR UniPathway; UPA00113; UER00528.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00714; GFAT; 1.
DR CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR CDD; cd05009; SIS_GlmS_GlmD_2; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR005855; GFAT.
DR InterPro; IPR047084; GFAT_N.
DR InterPro; IPR035466; GlmS/AgaS_SIS.
DR InterPro; IPR035490; GlmS/FrlB_SIS.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR NCBIfam; TIGR01135; glmS; 1.
DR PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR PANTHER; PTHR10937:SF10; GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2; 1.
DR Pfam; PF13522; GATase_6; 1.
DR Pfam; PF01380; SIS; 2.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
DR PROSITE; PS51464; SIS; 2.
PE 4: Predicted;
KW Aminotransferase {ECO:0000313|EMBL:KFP55718.1};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFP55718.1}.
FT DOMAIN 1..287
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
FT DOMAIN 359..498
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 530..671
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP55718.1"
FT NON_TER 681
FT /evidence="ECO:0000313|EMBL:KFP55718.1"
SQ SEQUENCE 681 AA; 76962 MW; E9238B67CD91B7FD CRC64;
TGIFAYLNYR VPRTRKEIFE TLIKGLQRLE YRGYDSAGVA IDGNNNEDKE RFIKLVKKRG
KVKALEEELY KQDDLDSKAE FETHFGIAHT RWATHGVPSA INSHPQRSDK RNEFVVIHNG
IITNYKDLRK FLESKGYEFE SETDTETIPK LIKYMYDNRE SEDTSFSALV ERVIQQLEGA
FALVFKSIHY PGEAVATRRG SPLLIGVRSK YKLSTEQIPV LYRTCNIENV KNICNSRMKR
LDSSTCLHAV GDKAVEFFFA SDASAIIEHT NRVIFLEDDD IAAVTDGKLS IHRLKRSASD
DPSRAIQTLQ MELQQIMKGN FSAFMQKEIF EQPESVVNTM RGRVNFESST VLLGGLKDHL
KEIRRCRRLI IIGCGTSYHA AVATRQVLEE LTELPVMVEL ASDFLDRNTP VFRDDVCFFI
SQSGETADTL MALRYCKERR ALTVGITNTV GSSISRETDC GVHINAGPEI GVASTKAYTS
QFVSLVMFGL MMSEDRISLQ KRRQEIISGL KSLPEMIKEV LSLDEKIHDL ALELYKQRSL
LVMGRGYNYA TCLEGALKIK EITYMHSEGI LAGELKHGPL ALIDKQMPVI MVIMKDPCFT
KCQNALQQVT ARQGRPIILC SKEDTESSKF AYKTIELPHT VDCLQGVLSV IPLQLLSFHL
AVLRGYDVDF PRNLAKSVTV E
//
