ID A0A091LH33_CATAU Unreviewed; 1262 AA.
AC A0A091LH33;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 35.
DE SubName: Full=Papilin {ECO:0000313|EMBL:KFP54465.1};
DE Flags: Fragment;
GN ORFNames=N323_12793 {ECO:0000313|EMBL:KFP54465.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP54465.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP54465.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP54465.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL318786; KFP54465.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LH33; -.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR CDD; cd22635; Kunitz_papilin; 1.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 5.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF179; PAPILIN; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 4.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00131; KU; 1.
DR SMART; SM00209; TSP1; 5.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 5.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 749..799
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 922..989
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1027..1117
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1120..1209
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1225..1262
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 545..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..628
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 18..54
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 22..59
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 33..44
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP54465.1"
FT NON_TER 1262
FT /evidence="ECO:0000313|EMBL:KFP54465.1"
SQ SEQUENCE 1262 AA; 138193 MW; 40ACE2C5CEE04305 CRC64;
RMKRQIDVWG SWGEWGKCSR SCGGGVSFRQ RRCYSQRTEG TSSCVGPTRS YRSCNVQSCP
EGSRDFRAEQ CAEFDGTEFQ GKKYKWLPYY GAPNKCELNC IPKGENFYYR HKEAVVDGTT
CEPGKQDICV EGVCQAVGCD NMLESAKKED KCLQCGGDGS TCYGVKGTFD VPSLPKGYNQ
IFIIPVGATS IRIKEVMPSR NFLAVKNVRG EYYLNGHWTI DFSRALQVAS TVMHYDRGSE
GDLAPELLHA QGPTTEPLVI ELISQEPNPG VQYEYYLPVQ GQASGYSWSY GSWSECSSEC
GGGFQSRLVF CTIDNEIYPD YMCRNKPQPD NNRTCGHQTC PQTKRWKTGE WGSCSATCGG
GTQTRSVYCV AFDGQSSQGV VDNAECMAFA QQPRSSQPCN MRQCATWSTG PWSECSASCG
EGVQTRTVTC RTQQGSQAQD FSCLMEPKPS ATQPCLKENC IQEIGWHVGD WGLCSKSCNS
GIRTRQVICA DGDSKFYSPE TCKAIQPQKP ATLGSCNMQP CYLPQQVPSM QDTMGYDVTR
QSLLTRYNPN NPATGSFSWG SRKNGQGSEQ RTSGQPNPEG TSGNHHIPST KDRGINLLPV
RWESRSRSSD SHQLSFSQDP TAGTGSQDCH RSPHGCCPDG HTPASGPLGR GCPFSTCRRN
RYGCCPDGVS AAQGPNNMGC PQYYRDVQVS RNQPTVATPA ASQALSQQHP SGECRSSMYG
CCFDNVASAS GPQGEGCLNR PNYPYPVICL LPSAHGPCTN WTTRWYFVTV VGKCNRFWYG
GCHGNKNSFA SEEECMRACR SSVGVSPLEH QPFSGTGALQ RQHTGSRSRT GDAQVPGPSE
RQSSSGQQVL PHEGKQWHKA FGADVSMTEG FGHHASPDSF PAWALHRGPR GEEGSRGANG
IAFSFRAILE EAKPSLVTAV VGQNVQLICK TSMSPFSRVE WMKDGRPVSS DRHTYQSDSS
LVISHVKLED AGTYTCLISD GRTESQQIQL QIIVIDNRSN KASCRSKLPL LPHCASSVAF
TPWQWCPKSW SKQLRMDKSE PSVVEADVGE RVRLPCTVEA SPALTIEWQK DGQPLSSPRH
RQQSDGALVI SRVSSEDVGF FTCIASNGRD QDQRQVLFRP RGELRITGLL PSITVPEGGT
AQLHCTVTGS NVNIRWSRNG VPMRADGHHI HLSQDGSLII SNVQEADEGS YTCSAYSSSN
SVSASTEVKV LRSRPSTTVN HVVDLSRECV DQPHLANCDL ILQAQLCSNE YYSSFCCASC
SR
//
