ID A0A091LIV9_CATAU Unreviewed; 2709 AA.
AC A0A091LIV9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Lysosomal-trafficking regulator {ECO:0000313|EMBL:KFP56796.1};
DE Flags: Fragment;
GN ORFNames=N323_09997 {ECO:0000313|EMBL:KFP56796.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP56796.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP56796.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP56796.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL327480; KFP56796.1; -; Genomic_DNA.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF163; LYSOSOMAL-TRAFFICKING REGULATOR; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1917..2023
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2028..2330
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2520..2554
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 94..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1005..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP56796.1"
FT NON_TER 2709
FT /evidence="ECO:0000313|EMBL:KFP56796.1"
SQ SEQUENCE 2709 AA; 305522 MW; 83C4F363E16B88F9 CRC64;
TSVREETKWA LQGIRLLEAL LTICLHSAST MQQKVEMEMF HQNTCVDDIL LQIREQLAQS
KVIETDLAKP LFDSLLRVAL GSLSADLDHS EEKIEKNHYT EKEPVSQPGD ISEETEESQC
CSLKLFAEEE GYEADSESNP DDSETKNEGA DTKAEPGCTG PSGYFNDLAE DINQGELMYP
EICMLELNLL SAGNASLDVL AHVFQSCLKI ISQKERNATV LIEQGAVKHL LGGFLNILTQ
TESSFHACQM VLVDLLVSLM SSQTRSEELT LFLRIFLEKT PCTEILLKGV LKIIETNIYM
NPLQYLAFPL LHGTNLSSSS SQKSASTSNS KTTALLKRVK FSQSKKETDS ENLSHQLLSS
WHVAPIHLPL VGQNCWPHMS EGFSVSLWFH LERAHETEKG KKIKRRSRLV AVRENSFDST
EETKSIGMEY LSLGDKLVED GCIHIISLGS KALMIQVWAD LNTGAFIFRM CVDPNDEMKA
GLLAQAESPE NVFLVGRWQH LAITYLQQPE GKKNIHGKLS LWVSGQRKCE INLDYALPRK
SSLSDSNKTF CMIGHCTSSQ EELLRLSGRW DLGNLLLFNG AKIGPEEAFY LYTCGPDFTS
VMPCKYGKTL TDCSKYISKE ILQCEQIKEL FMAKKEVDVG PLIESLAVVY TTCCPGQYTI
YEPVIRLKGQ VKTVPSQRPF SSKEVQSNVL DSHHLKKLQP VEYKTLQGIL HEIGGTGAFV
FLFARVVEIS SCEDTQALAL QLILSLTKYN QQRIQEMDNC NGYSMIHRVL IKPKCIVGFC
MLKTLLEGCC SDEILYINEN GQFMLDTDST AVIQDVQLLE KLLLDWKIWS KAKQGVWETL
LAALEILIRA NHHQQMFNIK QLLKAQVVHH FLLTCQVLQE HKEGHLASLC QEVCRSFVKI
IEEVLGSPPD LELLTLVFNF LLAVHPPTNT YVCHNPTNFY FSLHIDGKIF QEKVESLRYL
RNSSSGGKSI DSSAFVITTP TGFTALPLGG NTSKASVQQK ISSQAPKRLC KSLPPSPTSS
PQVHRKRLTE RMGRSTDDLQ IIGKHDYIDL QDRIGFVGSS ETIMRVQEQL FLSSCESAKT
VCDSELTSAE TFEDIAKEEE LSENGFESKE ADADLKCNEG DGAAAEPLLC RPDNLKGLPS
FQKSQSNFAG LGLAFSVHGG SSAIARWPSF ADKNVLPEDW ESLAFSSANE NTQKPSESPD
DRCTEDCLVL ICCGLYDLLR GVLLILPDSM LEDVMDKLIQ PDYLIVLVNH PSPLVQQGVI
KLLDAYFNRA RREQKEKFLK NRGFSLLANQ LYLHQGTQEV VECFLEMLFG RSVGLDEEFD
LEDVKNVGLF QKWCVIPVLG LIENSLYDNV LLHNCFCLLL QIINSCSKVA DLLLDNGLLY
VLCNTLAALN GLETNIPLND YKLLACDIQQ LLVAVAIHAC SSSGSQYFRV IEDLIVLLGH
LQNSKNARMQ NMAVVLQLRV LQAAIELIKT TVNQDAQEQA GSVPSPSAPH RAMFQKRKGI
AGSRKFSLAQ SDALLMKMRS LASEEFNMMM QRRMSQENPV QATETEFVQR LQRLTVLAVN
RLIYLASTEE CLDVLGITEN TSQSRLSASQ LEVPEEESQQ ELPSRTNSFL KEMFKMLVEG
IKVSIGTSRM NTPKQQWKRI LLSCKDTFRI QLGRLLVHNL SPARSLQVRK QALEMVHEVN
HQEIMRDCLS PTLQHGPKLV LYLYELMHNH SDEITKEEQR AAGDFVNTLK CCGYKCIPLS
PRPKPDLIKA LKEDQKKYEM EEGVNKAAWE KTMANNRQNL FQRLDTKSKD ISKIAGDITQ
AVSLSQGMER KKVIQHIRGM YKAELSASRH WQELVQQLTH DRALWYDPVY YPTSWQLDPT
EGPNRERRRL QRCYLTIPNK YLLPDRQKQE GVIKTPLSYL FEDKTHSSHS STVKDKAASE
HIRVNRRCIS VAPSRETAGE LLLGKCGMYF VEDNASDTIE NSSFHGETEP ASFSWTYEEI
KEVHKRWWQL RDNAVEIFLT NGRTLLLAFD NTKVRDDVYH NILTNNLPNL LEYGNITALT
HLWCTGQITN FEYLTHLNKH AGRSFNDLMQ YPVFPFILSD YTNETLDLND PSVYRNLVKP
IAVQSKEKED RYVDTYKYLE EEYRKGARED DPMPPVQPYH YGSHYSNSGT VLHFLVRLPP
FTKMFLAYQD QSFDIPDRTF HSTNTTWRLS SYESMTDVKE LIPEFFYLPD FLVNREGFDF
GVRQNGDRVN HVNLPPWARN DPRLFILIHR QALESDHVSQ TICHWIDLVF GYKQKGKASV
QAINVFHPAT YFGMDVSAVE DPVQRRALET MIKTYGQTPR QLFHAAHVSR PGSRLIMEGE
LPAAMGLLVQ FAFRETREHT KEIIYPSPLP WIKGLKWGEY VGSPSAPDPV VCFSQPHGER
FGSLQALPTK AICGLSRKFC LLMIYSKEQG VRSMHSTDIQ WSAILSWGYA DNILRLKSKQ
SEPPVNFIQS SQFHQVTSCA WVPDSCQLFT GSKSGVITAY MNRFTSNTPS EIEMESQVHL
YGHTAEITSL FVCKPYSIMI SVSKDGTCII WDLNRLCYVQ SLAGHKSPVT AVSASETTGD
IATVCDSVGG GSDLRLWTVN GDLVGHVHCR ESICSVAFSN QPEGVSVNVI AGGLENGVVR
LWSTWDLKPV REITFSKSAK PIVSLTFSCD GHHLFTANSD GNVIAWCRKD QQRLKLPMFF
SFLSSYAAG
//
