ID   A0A091LMG0_CATAU        Unreviewed;       885 AA.
AC   A0A091LMG0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 29.
DE   SubName: Full=Cullin-4B {ECO:0000313|EMBL:KFP57528.1};
GN   ORFNames=N323_09298 {ECO:0000313|EMBL:KFP57528.1};
OS   Cathartes aura (Turkey vulture) (Vultur aura).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX   NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP57528.1, ECO:0000313|Proteomes:UP000053745};
RN   [1] {ECO:0000313|EMBL:KFP57528.1, ECO:0000313|Proteomes:UP000053745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP57528.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KL329708; KFP57528.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091LMG0; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000053745; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF66; CULLIN-4B; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          530..758
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   885 AA;  101578 MW;  2647E02AED05D425 CRC64;
     MFPTGFSSPN PPAAAQEVRP ATDGNTSSSS SCKKRKLNNS SNSNSEREEF DSISSCASSP
     SKNTSSSSSS VITTSSCSSS GVASSNHHLQ KKLRFEDSVD FIGLDVKMAE ESSSSSSPAA
     SSQQQHQQQL KNKSLLISSV AVGHHANGLT KAASSTVSSF ANSKPGSAKK LVIKNFKDKP
     KLPENYTDET WQKLKEAVEA IQNSTSIKYN LEELYQAVEN LCSYKISANL YKQLRQICED
     HIKAQIHQFR EYPFVLFLKK IDKCWQDHCR QMIMIRSIFL FLDRTYVLQN SMLPSIWDMG
     LELFRTHIIS DQKVQNKTID GILLLIERER NGEAIDRSLL RSLLSMLSDL QIYQDSFEHR
     FLEETNRLYA AEGQRLMQER EVPEYLHHVN KRLEEEADRI ITYLDQSTQK PLIATVEKQL
     LGEHLTAILQ KGLNHLLDEN RIQDLSLLYQ LFSRVRGGVQ VLLQHWIEYI KAFGSTIVIN
     PEKDKTMVQE LLDFKDKVDH IIDVCFLKNE KFVNAMKEAF ETFINKRPNK PAELIAKYVD
     SKLRAGNKEA TDEELEKMLD KIMIIFRFIY GKDVFEAFYK KDLAKRLLVG KSASVDAEKS
     MLSKLKHECG AAFTSKLEGM FKDMELSKDI MIQFKQYMQN QNVPGNIELT VNILTMGYWP
     TYVPMEVHLP PEMVKLQEIF KTFYLGKHSG RKLQWQSTLG HCVLKAEFKE GKKELQVSLF
     QTLVLLMFNE GEEFSLEEIK QATGIEDGEL RRTLQSLACG KARVLTKSPK GKDVEDGDKF
     TCNDDFRHKL FRIKINQIQM KETVEEQAST TERVFQDRQY QIDAAIVRIM KMRKTLSHNL
     LVSEVYNQLK FPVKPADLKK RIESLIDRDY MERDKENPNQ YNYIA
//