ID A0A091LPJ0_CARIC Unreviewed; 623 AA.
AC A0A091LPJ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Metabotropic glutamate receptor 2 {ECO:0000313|EMBL:KFP61111.1};
DE Flags: Fragment;
GN ORFNames=N322_08193 {ECO:0000313|EMBL:KFP61111.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP61111.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP61111.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP61111.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR EMBL; KK505149; KFP61111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LPJ0; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF147; METABOTROPIC GLUTAMATE RECEPTOR 2; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00979; G_PROTEIN_RECEP_F3_1; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFP61111.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 421..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..623
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP61111.1"
FT NON_TER 623
FT /evidence="ECO:0000313|EMBL:KFP61111.1"
SQ SEQUENCE 623 AA; 70784 MW; 6542A05FCE0ABD12 CRC64;
GTHLSSSTQV ANLLRLFQIP QISYASTSAK LSDKSRYDYF ARTVPPDFYQ AKAMAEILRF
FNWTYVSTVA SEGDYGETGI EAFEQEARMR NICIATSEKV GRSMNKKTYD GVVRALLQKP
NARVVVLFTR SEDARELLAA AQRANMSFTW VASDGWGALE SVVAGSEAVA EGAITIELAA
YPIAEFAAYF RNLNPYNNSR NPWFREFWEQ KFKCSFHTQD CSRYSLKTGK FEPESKITFV
VNAVYAMAHS LHNMHQALCP NATKLCDAMK PVNGKRFYKD FMLNVNFDAP FRPSDPKRVV
RFDRYGDGIG RYNIFNYHRM DGRYRYQKVG YWAEGLILNT SLIPWAETSI PVSQCSDPCK
KNEIKSMQPG DICCWICIPC QPYEYLLDEF TCMDCGLGYW PNETLNGCYE LPQEYIRWKD
VWAIGPVTIS CLGFISTLFV FGVFMKNNDT PIVKASGREL CYILLTGVLM CYSMTFIFIA
KPSTEVCTLR RLGLGTSFAV CYSALLTKTN RIARIFSGVK EGVQRPRFIS PASQVVICMA
LVSCQLIIVI IWLLVETPGT GKETEPHKRY IVTLKCNNRD SNMLISLTYN VLLIVLCTVY
AFKTRKCPEN FNEAKFIGFT MYT
//
