ID A0A091LQT9_CARIC Unreviewed; 742 AA.
AC A0A091LQT9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};
DE Flags: Fragment;
GN ORFNames=N322_08906 {ECO:0000313|EMBL:KFP61551.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP61551.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP61551.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP61551.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU046415}. Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU046415}.
CC -!- SIMILARITY: Belongs to the transcription factor STAT family.
CC {ECO:0000256|ARBA:ARBA00005586, ECO:0000256|RuleBase:RU046415}.
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DR EMBL; KK506511; KFP61551.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LQT9; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd10375; SH2_STAT4; 1.
DR CDD; cd16854; STAT4_CCD; 1.
DR CDD; cd16848; STAT4_DBD; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.20.1050.20; STAT transcription factor, all-alpha domain; 1.
DR Gene3D; 2.60.40.630; STAT transcription factor, DNA-binding domain; 1.
DR Gene3D; 1.10.532.10; STAT transcription factor, N-terminal domain; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR001217; STAT.
DR InterPro; IPR046991; STAT4_CCD.
DR InterPro; IPR029839; STAT4_DBD.
DR InterPro; IPR035856; STAT4_SH2.
DR InterPro; IPR048988; STAT_linker.
DR InterPro; IPR036535; STAT_N_sf.
DR InterPro; IPR013800; STAT_TF_alpha.
DR InterPro; IPR015988; STAT_TF_coiled-coil.
DR InterPro; IPR013801; STAT_TF_DNA-bd.
DR InterPro; IPR012345; STAT_TF_DNA-bd_N.
DR InterPro; IPR013799; STAT_TF_prot_interaction.
DR PANTHER; PTHR11801; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; 1.
DR PANTHER; PTHR11801:SF19; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF01017; STAT_alpha; 1.
DR Pfam; PF02864; STAT_bind; 1.
DR Pfam; PF02865; STAT_int; 1.
DR Pfam; PF21354; STAT_linker; 1.
DR SMART; SM00964; STAT_int; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF47655; STAT; 1.
DR SUPFAM; SSF48092; Transcription factor STAT-4 N-domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159, ECO:0000256|RuleBase:RU046415};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU046415};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU046415};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU046415};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553,
KW ECO:0000256|RuleBase:RU046415};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU046415};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU046415}.
FT DOMAIN 570..672
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT NON_TER 742
FT /evidence="ECO:0000313|EMBL:KFP61551.1"
SQ SEQUENCE 742 AA; 84909 MW; 80E409B3150A4DCE CRC64;
MSQWSQVQQL EIKFLEQVDQ FYDDNFPMEI RHLLAQWIES QDWEAASNNE AMATILLQNL
LIQVDEQLDR VSQEKNLLLI HNLKRIRKLL QGKYHGNPMH IAVIISNCLR EERRILAAAS
MPVQGPLEKS LQNSVVSERQ RNVEHKVSAI KNSAQMTDQD VKYLEDLQEE FDFRYKTIQS
LEQSDKNSAL IKQEMLALQA MLNTLDYKRK EVLSKIGRVI HEIDMLMSNM LTEELLDWKR
RQQIACIGGP LHGGLDQLQN CFTLLAESLF QVRRQLEKLD ELLTRLTYDG DPIPVQRPQL
LEKVNFLLYN LFRNSFVVER QPCMPTHPQR PMVLKTLIQF TVKLRLLIKL PELNYQIRVK
ATIDKNVSTV SNRRFVLCGT HVKAMNMDES ANGSLSVEFR HLQPKEMKSS AGSKGNEGPH
MVTEELHSIS FETQVCLYGL TINLETSSLP VVMISNVSQL PNAWASIIWY NLSTNDPQNL
SFFNNPPAAT LSQLLEVLSW QFSSYVGRGL NSEQLNMLAE KLTGQQASYN DYQLTWAKFC
KEHLPGKSFT FWVWLEAILD LIKKHILPLW IDGYVMGFVS KEKERILLKD KTPGTFLLRF
SESNLGGITF TWVDQLENGD VTFHSVEPYN KGRLSALPFA DILRDYKVIM ADNVPENPLK
YLYPDIPKDK AFGKHYSCQP NEVSKPSDGG GKGYVPSVFI PVSKILNDST DPHSPSDLLP
MSPSVYAVLR EHLSPTVIET AV
//
