ID A0A091LSN9_9GRUI Unreviewed; 409 AA.
AC A0A091LSN9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Lipase member M {ECO:0000313|EMBL:KFP45801.1};
DE Flags: Fragment;
GN ORFNames=N324_05000 {ECO:0000313|EMBL:KFP45801.1};
OS Chlamydotis macqueenii (Macqueen's bustard).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Otididae; Chlamydotis.
OX NCBI_TaxID=187382 {ECO:0000313|EMBL:KFP45801.1, ECO:0000313|Proteomes:UP000053330};
RN [1] {ECO:0000313|EMBL:KFP45801.1, ECO:0000313|Proteomes:UP000053330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N324 {ECO:0000313|EMBL:KFP45801.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701}.
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DR EMBL; KK764014; KFP45801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091LSN9; -.
DR Proteomes; UP000053330; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF168; LIPASE; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053330};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..409
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001876486"
FT TRANSMEM 283..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..107
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 182
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 355
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 384
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP45801.1"
FT NON_TER 409
FT /evidence="ECO:0000313|EMBL:KFP45801.1"
SQ SEQUENCE 409 AA; 46653 MW; 2213111185ED28ED CRC64;
TMMWLFVSIA CLMCTSEKSD GSPEVSMDVG EIVRYHGYPY EEHEVMTDDG YYLTVQRIPH
GRDNSASTSI SHKAEAQGSS MFCPTPKPAV LLQHGLVLEG SNWVTNLPNS SLGFILADAG
YDVWIGNSRG NSWSRKHKEF EFHHKEYSAY SFHEMAMYDL PATINYILQK TGQEQLYYVA
YSQGTTTGFI AFSSIPELDH KIKMFFALAP ITTNSNMKSP LVRLFDLPEV LVKLILGRTV
VFDKGELLQQ VISSLCSYTI FKRFCSLVLY LPGGFTNSLN VVLFFPIISI VFLMVPSNAW
VINTVLLLFQ VYQTGEFKYY DYGSDNMLHY NQITPPFYEL ENMKAPLAAW YGGKDWISAP
EDVNITLPRI TNVAYQKYIP EFVHFDFLWG VQAYEQVYKE ILELMEKSA
//
