ID A0A091M256_CATAU Unreviewed; 696 AA.
AC A0A091M256;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 26.
DE SubName: Full=Protein-glutamine gamma-glutamyltransferase 6 {ECO:0000313|EMBL:KFP52646.1};
DE Flags: Fragment;
GN ORFNames=N323_04825 {ECO:0000313|EMBL:KFP52646.1};
OS Cathartes aura (Turkey vulture) (Vultur aura).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP52646.1, ECO:0000313|Proteomes:UP000053745};
RN [1] {ECO:0000313|EMBL:KFP52646.1, ECO:0000313|Proteomes:UP000053745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP52646.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRSR:PIRSR000459-2};
CC Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR000459-2};
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR EMBL; KL308677; KFP52646.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091M256; -.
DR Proteomes; UP000053745; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR InterPro; IPR023608; Transglutaminase_animal.
DR InterPro; IPR013808; Transglutaminase_AS.
DR InterPro; IPR008958; Transglutaminase_C.
DR InterPro; IPR036238; Transglutaminase_C_sf.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR11590:SF50; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 6; 1.
DR Pfam; PF00927; Transglut_C; 2.
DR Pfam; PF01841; Transglut_core; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR PIRSF; PIRSF000459; TGM_EBP42; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49309; Transglutaminase, two C-terminal domains; 2.
DR PROSITE; PS00547; TRANSGLUTAMINASES; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|PIRSR:PIRSR000459-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000459-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW Transferase {ECO:0000313|EMBL:KFP52646.1}.
FT DOMAIN 266..358
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT ACT_SITE 274
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 332
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT ACT_SITE 355
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-1"
FT BINDING 395
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 397
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 444
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT BINDING 449
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000256|PIRSR:PIRSR000459-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP52646.1"
FT NON_TER 696
FT /evidence="ECO:0000313|EMBL:KFP52646.1"
SQ SEQUENCE 696 AA; 78675 MW; 6A35B4AD26BAEA41 CRC64;
FTDLTPTHIS WQPSVNAGTH HTDRYANTEL TVRRGQAFTI TLYFNRPKHT GESLAFVTEI
GPSPSESHRT KAVFNLSEVG ASGWSAVQGP SESGYMNFTI SSPANAVIGR YNLTLQVTSG
NKIFSRFLGQ FVLLFNPWCP GDDVYMANEN ERQEYVLNEN GIIFVGNAKY IEARGWYYGQ
FQDHLLNICL TMLDLSLYYR QDPAIDVSRR GDPKYVGRVI SSMINGNDND NGVLLGKWQG
SFHSHENPSR WDGSVVILQK WRQDNYKPVQ YGQCWVFAGV MCTVLRCLGI PTRLVSNFNS
AHDVDRNLSI DKYYDSSGKS LNISKDSTWD YHVWNESWFT RPDLGTSYNG WQVLDATPQE
QSKGLFQCGP TSVIAIKEGD VDLDYDTLFV YTEVNADCNR WIVYNDGTKK RVYCDTEIIG
RFISTKAVGS NSRVDVTYNY KYPEGSSEER QVYKKALAKI FGSNITEGHT ESPDERSSET
IRNPGISGKF KLAEPPVFGK DITLILILNN LSFDHKTVKV DMSASTILYT RRAVAEILKA
TTSVDLDSKQ GKHIQLKIPY SYYGKYLTTD KRIQVTALCE VMHMHGVKLL VEKTIILEDT
NIIIKIPRRV VVNKAVTLEI SYANPLPEPV NRCVLLVTLM NQQVKIHLAR LAPRERSKIY
FEFTPRRTGP LQLQVDFSCD KFSHVKGFVT IAVAPA
//
