ID   A0A091M5C9_CATAU        Unreviewed;       708 AA.
AC   A0A091M5C9;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=receptor protein-tyrosine kinase {ECO:0000256|ARBA:ARBA00011902};
DE            EC=2.7.10.1 {ECO:0000256|ARBA:ARBA00011902};
DE   Flags: Fragment;
GN   ORFNames=N323_01794 {ECO:0000313|EMBL:KFP53731.1};
OS   Cathartes aura (Turkey vulture) (Vultur aura).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Accipitriformes; Cathartidae; Cathartes.
OX   NCBI_TaxID=43455 {ECO:0000313|EMBL:KFP53731.1, ECO:0000313|Proteomes:UP000053745};
RN   [1] {ECO:0000313|EMBL:KFP53731.1, ECO:0000313|Proteomes:UP000053745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N323 {ECO:0000313|EMBL:KFP53731.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC         [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC         COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC         ChEBI:CHEBI:82620, ChEBI:CHEBI:456216; EC=2.7.10.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001171};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; KL314438; KFP53731.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091M5C9; -.
DR   Proteomes; UP000053745; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd00063; FN3; 2.
DR   CDD; cd00064; FU; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   Gene3D; 3.80.20.20; Receptor L-domain; 2.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR006211; Furin-like_Cys-rich_dom.
DR   InterPro; IPR006212; Furin_repeat.
DR   InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000494; Rcpt_L-dom.
DR   InterPro; IPR036941; Rcpt_L-dom_sf.
DR   Pfam; PF00757; Furin-like; 1.
DR   Pfam; PF01030; Recep_L_domain; 2.
DR   SMART; SM00261; FU; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
DR   SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Receptor {ECO:0000313|EMBL:KFP53731.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053745};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          588..690
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP53731.1"
FT   NON_TER         708
FT                   /evidence="ECO:0000313|EMBL:KFP53731.1"
SQ   SEQUENCE   708 AA;  80809 MW;  C627E4F176A608F9 CRC64;
     VCRSMDIRNN LTRLNMLENC TVIEGHLQIL LMFKTKPEDF RELSFPKLTM ITDYLLLFRV
     YGLESLKGLF PNLTVIRGTH LFFNYALVIF EMVHLKEIGL YNLMNITRGA VRIEKNNELC
     YLSTIDWSRI LDSVEDNYIV ANKDDKEECG DVCPGTVKGK SNCPPTVING IFIERCWTHD
     RCQRVCPPAC KSQGCTSDGQ CCHSECLGDC TEPNNPEKCV ACRNFYLEGK CVDTCPPGYY
     RFEGWRCVTF SFCQELHNKC KNARESGCHV IHNNECVHEC PSGYIMNSSN LHCTPCAGPC
     PKVCDYGKEK TIDSVTSAQE LRGCTVVNGS LVINIRGGNN IAAELEANLG LIEEISGYLK
     IRRSYALVSL SFFRKLHLIR GETLEAGNYS FYALDNQNLR QLWDWSKHNL TIARGKLFFH
     YNPKLCLSEI HKMEEISGTK GRQERNDIAL KTNGDQASCE NELLKFSSIR TSHDKILLKW
     EPYWPPDFRD LLGFMLFYKE APYQNVTEFD GQDACGSNSW TVVDVDPPPR SNEPKAQAQP
     GWLLRGLKPW TQYAVFVKTL VTFSDERRTY GAKSEIIYVQ TNATVPSVPL DPISVSNSSS
     QIILKWKPPS EPNGNITHYL VFWQQQAEDS ELYELDYCLK GLKLPSRTWS PPFESEDPQK
     YNQSENEDVS GECCSCPKTD SQIQKELEES AFRKTFENYL HNEVFVPR
//