ID A0A091ML39_9PASS Unreviewed; 1241 AA.
AC A0A091ML39;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=N310_07155 {ECO:0000313|EMBL:KFP75303.1};
OS Acanthisitta chloris (rifleman).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC Acanthisitta.
OX NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP75303.1, ECO:0000313|Proteomes:UP000053537};
RN [1] {ECO:0000313|EMBL:KFP75303.1, ECO:0000313|Proteomes:UP000053537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP75303.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; KK829407; KFP75303.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091ML39; -.
DR Proteomes; UP000053537; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd18016; DEXHc_RecQ2_BLM; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR012532; BDHCT.
DR InterPro; IPR032439; BDHCT_assoc.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF08072; BDHCT; 1.
DR Pfam; PF16204; BDHCT_assoc; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053537}.
FT DOMAIN 502..677
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 703..850
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1038..1118
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 11..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 318..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1115..1241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1117..1155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP75303.1"
FT NON_TER 1241
FT /evidence="ECO:0000313|EMBL:KFP75303.1"
SQ SEQUENCE 1241 AA; 135816 MW; C6AAF6065515C2D0 CRC64;
EKKYCRARVL SLKGPCRSPP RQSPRDAGGH GEAAPDALSE PLSQQSLICL EESAPRADNA
AAGQDPWEDS PAELVRDEDR AEARTGQAGD SPSRWDKADT GLVAGAEFED DDYLDVVPPS
PEEELPPFSP SVHNVSSIFK GSPAQGRCSA GSTETGPGKV PTTQPGADPS AGDAGEDVAQ
QLYSVMEAVC ELVDAIPLQE LQSLSCARAL LQHRDLRRKL LANSASLNHS GLNTLPRSRK
TPVGQGPGAS PGAAPGFGQS WSFSLDRDSL KSVTLLSMCS VHSSNSSAKA NQTLNTSCAS
KQSVVEITCP GSTVLSFPKG SGSGGGSLRL SLCSEPSSSS SWGESPGVRD GKQPLTSTAL
KAQSTAPTAS PAANSLGTND PDFDLDHFDI DDFDEDWESS VSVSAPEAPS TPLYQPSKEG
PPAKSLLSKI MSRAQGSAVG SNPSAPKSSF PMATKNHPDP VVHNPALERF RGMKFSHSEE
MMTIFHRKFG LHYFRTNQLE AINAALLGED CFILMPTGGG KSLCYQLPAC VSAGVTIVIS
PLRSLIIDQV QKLKTLDIAA TYLTGDRTDA DASKIYMQLS KKDPVIKLLY VTPEKVCASS
RLMSALENLY DRKLLARFVI DEAHCVSQWG HDFRQDYKRL NMLRRKFRSV PMMALTATAN
PRVQKDIQNQ LEMLKPQVFT MSFNRHNLKY DVLPKKPKKV AIDCLEWIKK YHPHDSGIIY
CLSRHECDTT AAILQKEGLA ALAYHAGLTD SSRDLVQQKW VNQEGCQVIC ATIAFGMGID
KPDVRYVIHA SLPKSIEGYY QESGRAGRDG EMSHCLLFYS YSDVTRLRRL ILMEKDGNSH
TRQTHFNNLY SMVHYCENVV DCRRIQLLAY FGETNFNPTF CKDHPEVICD NCSRKKDYKS
RDVTEDVRSI VRFVREHCGA VGQLNRKRNA GLGRYTLNMM VDIFLGATSA KIQTGIFGKG
AAYSRHNAER LFRKLVLDKI LDEDLYITAN DQAVAYVILG EKAQAVLDGS LQVQFHETEN
ASAIRRQRAS MAKMSRREEM VKQCLSELTD TCKTLGKVFD VHYFNIFSTS TLKKIAETLS
SDVEVLLQID GVTEDKLEKY GAEIIKVMDK YSEQSIPEDT ACPSADTALG STSTPGSDGE
AEDAGTTSSY FGNNTNQRRK RKRPPNARDS KRKKTSAGGS QQFHPRGGYS RYRRTKRPPS
SKAAAPFGPS SASQGAAGKL GMMALPKPKS RHFLQPSYSV L
//
