ID A0A091MRZ6_9PASS Unreviewed; 979 AA.
AC A0A091MRZ6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=SLIT-ROBO Rho GTPase-activating protein 2 {ECO:0000313|EMBL:KFP80243.1};
DE Flags: Fragment;
GN ORFNames=N310_01618 {ECO:0000313|EMBL:KFP80243.1};
OS Acanthisitta chloris (rifleman).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC Acanthisitta.
OX NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP80243.1, ECO:0000313|Proteomes:UP000053537};
RN [1] {ECO:0000313|EMBL:KFP80243.1, ECO:0000313|Proteomes:UP000053537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP80243.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK836635; KFP80243.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091MRZ6; -.
DR Proteomes; UP000053537; Unassembled WGS sequence.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07682; F-BAR_srGAP2; 1.
DR CDD; cd04383; RhoGAP_srGAP; 1.
DR CDD; cd11955; SH3_srGAP1-3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035648; srGAP1/2/3_SH3.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14166:SF6; SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 2-RELATED; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000053537};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..302
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 501..686
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 735..794
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 159..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 796..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 348..382
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 159..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP80243.1"
FT NON_TER 979
FT /evidence="ECO:0000313|EMBL:KFP80243.1"
SQ SEQUENCE 979 AA; 111080 MW; 98CEACC0336A95F3 CRC64;
EIRAQLVEQL KCLDQQCELR VQLLQDLQDF FRKKAEIEMD YSRNLEKLAE RFLAKTRSTK
DQQFKKDQNV LSPVNCWNLL LNQVKRESRD HTTLSDIYLN NIIPRFVQVS EDSGRLFKKS
KEVGLQLQED LMKVLNELYT VMKTYHMYNA DSISAQSKLK EAEKQEEKQI GKSVKQEDKQ
TPRSPDSTSN VKFEEKHVRR SSVKKIEKMK EKRQAKYTEN RLKAIKARNE YLLALEATNA
SVFKYYIHDL SDLIDCCDLG YHASLNRALR TFLSAELNLE QSKHEGLDAI ENAVENLDAN
SDKQRLMEMY NNVFCPPMKF EFQPHMGDMV SACFLLQESQ LCAQQPVQSE LVQRCQQLQS
RLSTLKIENE EVKKTMEATL QTIQDIVTIE DFDVSDCFQY SNSMESVKST VSETFMSKPS
IAKRRANQQE TEQFYFTKMK EYLEGRNLIT KLQAKHDLLQ KTLGESQRTD CSLASQAFLV
FILCFPSCLS SLSILIALLY ISLGQDSSQA IPLVVESCIR FISRHGLQHE GIFRVSGSQV
EVNDIKNAFE RGEDPLAGDQ NDHDMDSIAG VLKLYFRGLE HPLFPKDIFH DLIACVTMDN
LQERALHVRK VLLTLPKTTL IVMRYLFAFL NHLSQFSEEN MMDPYNLAIC FGPTLMSVPE
GHDQVSCQAH VNELIKTIII QHENIFPGPR DLEGPLYSRG GNTEDYCESP HGERASTEDS
VPDVTAEHHT SDDECEPIEA IAKFDYLGRT ARELSFKKGA SLLLYQRASD DWWEGRHNGI
DGLIPHQYIV VQDTEDGISE RSSPKSEIEI NSEPPEEKVT ARAGASCPSG GHVADIYLAN
INKQRKKPES GSIRRAFRQS DSHGLGSSLA EPASPGAIAG SRPSSQPIMS QSLPKEVPDK
CSISGHGSLN SISRHSSLKN RMDSPQIRKA VTAGRSKSFN NHRPMDPEVI AQDIEATMNS
ALNELRELER QSSVKHTPD
//
