ID   A0A091MSH1_9PASS        Unreviewed;      1741 AA.
AC   A0A091MSH1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Phosphatidylinositol 4-kinase alpha {ECO:0000313|EMBL:KFP79407.1};
DE   Flags: Fragment;
GN   ORFNames=N310_09453 {ECO:0000313|EMBL:KFP79407.1};
OS   Acanthisitta chloris (rifleman).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC   Acanthisitta.
OX   NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP79407.1, ECO:0000313|Proteomes:UP000053537};
RN   [1] {ECO:0000313|EMBL:KFP79407.1, ECO:0000313|Proteomes:UP000053537}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP79407.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type III PI4K
CC       subfamily. {ECO:0000256|ARBA:ARBA00006209}.
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DR   EMBL; KK835077; KFP79407.1; -; Genomic_DNA.
DR   Proteomes; UP000053537; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00871; PI4Ka; 1.
DR   Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001263; PI3K_accessory_dom.
DR   InterPro; IPR042236; PI3K_accessory_sf.
DR   InterPro; IPR045495; PI4K_N.
DR   InterPro; IPR015433; PI_Kinase.
DR   PANTHER; PTHR10048:SF15; PHOSPHATIDYLINOSITOL 4-KINASE ALPHA; 1.
DR   PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR   Pfam; PF00613; PI3Ka; 1.
DR   Pfam; PF19274; PI4K_N; 2.
DR   SMART; SM00145; PI3Ka; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   PROSITE; PS51545; PIK_HELICAL; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:KFP79407.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053537};
KW   Transferase {ECO:0000313|EMBL:KFP79407.1}.
FT   DOMAIN          1475..1663
FT                   /note="PIK helical"
FT                   /evidence="ECO:0000259|PROSITE:PS51545"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFP79407.1"
FT   NON_TER         1741
FT                   /evidence="ECO:0000313|EMBL:KFP79407.1"
SQ   SEQUENCE   1741 AA;  196396 MW;  2218646FA0B5DD69 CRC64;
     QVQKLLCMCP VDFHGIFQLD ERRRDAVIAL GIFLIESDLQ HKDNVVPYLL RLLKGLPKVQ
     WIEESNARKG RGLLPVAENF SFCLVTLLSD VAYRDASLRE QILDAILQVM QFLLGMCQTP
     QMHDKEYLCK YAVPCLMGIS RAFGRYSNSE EALLSKLFPK IPPHSLRVPE ELEGIRRRSF
     NDFRSILPNS LLTVCQEGTL KRKASSVSSI SQVSPERGIP PPSSPGGSAI HYFDGSYLPD
     GSAVDPDYYF CTISSSFSVS PLFNGINNKE FNIPLEMLRQ LLNMVKQIVG DSLLKTLDAV
     VAEVIETGAS TDLYYKAFSD PLYLAQFKML RDTLYYMKDL PNSFVKEIYD FVLEQLNSSQ
     SELQKILHDA DRVQHELGPL KLRCQASAAC VDLMVWAVKD EQGAENLCIK LSEKLQSKSS
     SKVIIAHLPL LVCCLQGLGR LCERFPVVVH SVNPSLRDFL VIPSPVLVKL YKYHSQYHTV
     GGNDIKISVT NEHSESTLSV MPGKKSQQSL YEQLRDIAIE NICRCLKAGL TIDSVIVEAF
     LASLSNRLYI SQESDKEAHL IPDHTIRALG HIAVALRDTP KMMEPILQIL QQKFCQPPSH
     LDVLIIDQLG CMVITGNQYI YQEVWNLFQQ ISVKASSVVY SATKDYKDHG YRHCSLAVIN
     ALANIAANIQ GEHLVDELLM NLLELFVQLG LEGKRASERA SEKGPALKAS SSAGNLGVLI
     PVIAVLTRRL PPIKEAKPRL QKLFRDFWLY SVLMGFAVEG SGLWPEEWYE GVCEIATKSP
     LLTFPSKEPL RSVLQYNSAM KNDTVTSAEL NELRSTIINL LDPPPEVSAL INKLDFAMST
     YLLSVYRLEY MRVLRSTDQD RFQVMFCYFE DKAIQKDKSG MMQCVIAVAD KVFEAFLSMM
     ADKPKTKENE EELERHAQFL LVNFNHIHKR IRRVADKYLS GLVDKFPHLL WSGTVLKTML
     DILQTLSLSL SADIHKDQPY YDIPDAPYRI TVPDTHEARE SIVKDFAARC GMILQEAMKW
     APSVTKSHLQ EYLNKHQNWV SGLSQHTGLA MATESVLHFA GYNRQNTTLG ATQLTERPTC
     VKKDYSNFMA SLNLRNRYAG EVSGMIQFSN ATGRASDLNK LMVKELNVAL ESGHTEFYTQ
     AMFKLTALLI SSKDCDPQLL HHLCWGPLRM FNEHGMETAI ACWEWLLAAK NGIEVPFMRE
     MAGAWQMTVE QKVGLFSAEQ KEADPLAASE ESQPRPCPPE VTPHYIWIEF LVQRFEIAKY
     CSSDQIEILP APXXXXXGGA KGSLNRHVAA IGPRFKLLTL GLSLLHADVV PNATIRNVLR
     EKIYSTAFDY FSCPSKFPTQ GEKRLREDIS ILIKFWTAMF SDKKYLTASQ LVPPDNQDTR
     SNLDINVGSR QQATQGWINT YPLSSGMSTI SKKSGMSKKT NRGTQLHKYY MKRRTLLLSL
     LATEIERLIT WYNPLSSPEL ELDQTGESSV ANWRSKYISL SEKQWKDNVN LAWSISPHLA
     VQLPTRFKNT EAIGTEVTRL VRLDPGAVSD VPEAIKYLVT WHTIDADAPE LSHVLCWAPT
     DPPTGLSYFS SMYPPHPLTA QYGVKVLRSF PPDAILFYIP QIVQALRYDK MGYVREYILW
     AAAKSQLLAH QFIWNMKTNI YLDEEGHQKD PDIGELLEQL VEEITGSLSG PAKEFYQREF
     DFFNKITNVS AIIKPFPKGD ERKKACLSAL SEVKVQPGCY LPSNPEAIVL DIDYKSGTPM
     Q
//