ID A0A091N1G2_CARIC Unreviewed; 592 AA.
AC A0A091N1G2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Interleukin-6 receptor subunit beta {ECO:0000313|EMBL:KFP67615.1};
DE Flags: Fragment;
GN ORFNames=N322_09722 {ECO:0000313|EMBL:KFP67615.1};
OS Cariama cristata (Red-legged seriema).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Cariamiformes; Cariamidae; Cariama.
OX NCBI_TaxID=54380 {ECO:0000313|EMBL:KFP67615.1, ECO:0000313|Proteomes:UP000054116};
RN [1] {ECO:0000313|EMBL:KFP67615.1, ECO:0000313|Proteomes:UP000054116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N322 {ECO:0000313|EMBL:KFP67615.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00008921}.
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DR EMBL; KK524532; KFP67615.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091N1G2; -.
DR Proteomes; UP000054116; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003529; Hematopoietin_rcpt_Gp130_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF83; INTERLEUKIN-6 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF00041; fn3; 1.
DR SMART; SM00060; FN3; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS01353; HEMATOPO_REC_L_F2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KFP67615.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..104
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 197..291
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 393..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP67615.1"
FT NON_TER 592
FT /evidence="ECO:0000313|EMBL:KFP67615.1"
SQ SEQUENCE 592 AA; 65239 MW; 28681E92E2787B36 CRC64;
SEPSKGPSIW RIIDASHSPA SWTVRLMWKA LEPFEANGVV LQYEVTVRAK SSLSSPPQKY
NVNTTNLTLK LQNGTYEVTV IAHNRVGASP PSVLLIPASN SKAPVKNVRT LPKDGKLWIG
WTAPNSYVLK YVIEWCLVSS SSDCIIEWQN EPGNVQGTYL KGDIKPFKCY LITVYPLYAD
GQGSGQSVKA YLLQDRPSKG PTVQTKKVGK AEAVLTWNHL TVDEQNGFIR SYTIFYKTID
GNETAVTVDP SKTEYTLSSL TSDTLYTVRM MAYTDEGGRS GPDFTFTTQK FGKGEIEAIV
VPVCLAFLLI VLLGVLFCFN KRDLIKKHIW PIVPDPSKSN IAQWSPQVPA KHNFSSKDQM
YPEGSFTDVS VVEIEADDKK SFSEQDLKPF DLLKKEKSTS EGHSSGIGGS SCMSSPRQSV
SDSDEGETTQ NTSSTVQYST VVLNGYRDQT PVQVFSRSES TQPLLDSEER SEDHAGGGDS
TTQGQQYFKQ NGGQDETNTD RPCFERTKQI TPANEGDLVG FVQLQISGQS SQPLGLGLEK
NTQEAALSHV LQTSTEGQTV RPETVERNPL SVDEMPKSYL PQTVRQGGYM PQ
//
