ID A0A091N2I4_APAVI Unreviewed; 965 AA.
AC A0A091N2I4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|EMBL:KFP83142.1};
DE Flags: Fragment;
GN ORFNames=N311_02184 {ECO:0000313|EMBL:KFP83142.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP83142.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP83142.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP83142.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL375038; KFP83142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091N2I4; -.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01260; PH_CNK_mammalian-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010599; CNK2/3_dom.
DR InterPro; IPR017874; CRIC_domain.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF12; CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2; 1.
DR Pfam; PF06663; CNK2_3_dom; 1.
DR Pfam; PF10534; CRIC_ras_sig; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51290; CRIC; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KFP83142.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244};
KW Transferase {ECO:0000313|EMBL:KFP83142.1}.
FT DOMAIN 18..112
FT /note="CRIC"
FT /evidence="ECO:0000259|PROSITE:PS51290"
FT DOMAIN 149..231
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 500..599
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 345..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP83142.1"
FT NON_TER 965
FT /evidence="ECO:0000313|EMBL:KFP83142.1"
SQ SEQUENCE 965 AA; 108974 MW; A44B3F6F0385A79F CRC64;
LAACRLLSPQ NYGLETENLR TLSHKLNASA KNLQNFITGR RRSGHYDGRA SRRLPNDFLT
SVVDLIGAAK NLLAWLDRSP FVSVTEYSLL KNNIVQLCLE LTTIVQQDCT VYETENKILH
VCKTLSGICD HIISLSSDSL VSQSAHLEVV HLTSIMPSEG LGMYIKSTYD GLHVITGTTE
NSPADQCKKI HAGDEVIQVN HQTVVGWQLK NLVNALREDP NGVILTLKKR PQNTLVSAPA
LLKNVRWKPL ALQPVIPTSP TSSSTTPTST MGISSKMDNS ALQDVFILSP MSGLYGPRDE
IGIMSCDDIS KFGKSGMKGS ESPSYFLEHE SGKYYTLIEG EGHPVGSEYE RSRATGVRRR
EKTPTHGDLR PVSMPTEYSW IGESKEQNMY KRGSRDSENS LLRYLSDDKI LVIQEEPLTQ
KDNKRDTGRR SRKKGKTTSN PNYPISPSML ASTLNVRLEP GQQDILNFSL AENNTVPLYH
VRSSLTSGSR RRISCKDLGH GDCEGWLWKK KDAKGYFTQK WKKYWFILKD SSLYWYTNQN
DEKAEGFISL PEFRIDRAIE CRRKHAFKAC HPKIKSFYFA TDCLEEMNRW MNRLGLAAIG
YTPDDKDIHP DEDYWSESDQ DDVDGSLTLK QEGSSTLCDS YHRTPSVNSS SPFPEAKHGR
HFSSESTYSH SSAEDSRQEV PSSTSGCRPP YRERRSWQDL IETPLTSSGL HFLQTVPPDA
EYVSGRPGMS PERRRQATLP VQRRHNYEQD GPFPLVECQR GASSHSRPQK QRSQSLPRNR
EVRGKGRAKS IEGTDDSLEE TVLIRRHNSF CAEGKLSEMG FFIYFFSENV KEIGENTDGL
QELYKSLEQA SLSAFGEQRP STKQEFRKSF VKRCNDPVIN EKLHHIRVLK STLKAKEGDL
TVINSLLDDP NLTSKKFKDW KLKNYEFFLD ICEYSAAVKS QNGASELASS APMLTHTHSF
IETHV
//
