ID A0A091N3L6_APAVI Unreviewed; 2077 AA.
AC A0A091N3L6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Polycystic kidney disease and receptor for egg jelly-related protein {ECO:0000313|EMBL:KFP83547.1};
DE Flags: Fragment;
GN ORFNames=N311_06657 {ECO:0000313|EMBL:KFP83547.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP83547.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP83547.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP83547.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the polycystin family.
CC {ECO:0000256|ARBA:ARBA00007200}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; KL375627; KFP83547.1; -; Genomic_DNA.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd01752; PLAT_polycystin; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002859; PKD/REJ-like.
DR InterPro; IPR013122; PKD1_2_channel.
DR InterPro; IPR003915; PKD_2.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR042060; PLAT_polycystin1.
DR InterPro; IPR046791; Polycystin_dom.
DR InterPro; IPR014010; REJ_dom.
DR PANTHER; PTHR10877:SF150; POLYCYSTIC KIDNEY DISEASE AND RECEPTOR FOR EGG JELLY-RELATED PROTEIN; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF20519; Polycystin_dom; 1.
DR Pfam; PF02010; REJ; 1.
DR PRINTS; PR01433; POLYCYSTIN2.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR PROSITE; PS50095; PLAT; 1.
DR PROSITE; PS51111; REJ; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:KFP83547.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1008..1029
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1217..1237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1249..1274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1397..1420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1432..1454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1529..1551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1790..1810
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1909..1936
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1971..1996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..743
FT /note="REJ"
FT /evidence="ECO:0000259|PROSITE:PS51111"
FT DOMAIN 1054..1171
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT REGION 1314..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1337..1368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1628..1645
FT /evidence="ECO:0000256|PIRSR:PIRSR603915-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP83547.1"
FT NON_TER 2077
FT /evidence="ECO:0000313|EMBL:KFP83547.1"
SQ SEQUENCE 2077 AA; 235191 MW; AA0E026771BA3B86 CRC64;
FVAKVNCTRS ALPPSLVRVR VDNYAAKTIE APVSCQQTSC YIRTLHIRKP ANTSVLHRKR
QTYFTLSVSL IVECPFTISI KPLWQIYPVP DMSTGPDWSN PVDTTRMHGT DMVILTVPRY
SLNYGLYLFH FTAEVTLIET NTVFWGTDSV YVRIEGSDLV AHITGGTYRK VGFSANWTLD
GSGSFDPDSL DRQKEITFTW YCTKEMSDYN SMKISLGNKC HPAQRDLKWI TPSGPVQTVT
AESLPGNTEY HFRLEVRKGE RWNYADQTVA VQLSSPPELL LNVACLENCG STLIPTERFI
LSGKCVNCKS NNHPVYYWSL FSENSTEINF DWSSKTSTGR WGPYLSIHAL TFTKAAHRSY
ILMLKVTTRD GRSSLYRHAF KVNSPPTSGK CTINPRQGMA FQTKFIVQCR GFYDSNLPLT
YKVIVASDIP KTTKVTSVEE NTFGTILYFG YKPETPPTFL PVGAPSRKYV LTLYVQVCDS
LGAFTQVNLH VRVRNPVTRR PLAVVFDELL DSVRGSSSPM TSYLQIGDYF SAGYLAYLAG
SVLKYIKATP NLKLPKAQLR ENLIKASLNI SVENTMEVNQ IAASLSQVTE EADEVNIRSQ
NLVIRKLMEV TGVLKILRNE SQWSEESEIQ TSGILSCLSN ILSAALLHRS NVNVNGIKQA
FSIMENLTEI VFQGKVPGET DTVMKTKHWN ITLMKDEHWN ISDAFSTRGT CKNCFYPSLK
KGNYSELDPD AVISTAVFEF DENPFPWLGY TSEIGTTILG FKMAETKPNG DLLEIMPEGA
EITVARKDKA SSAFQLAMGP DKTQAYTTGG FSLEVNRNTK SIYIQILTKL KVTFKVLVFT
GANITDAHPI ASFAAFHNTT TVAINETASN DCKIKAPYII CLPESLLKAT AEGSGTETYN
ISIVLVAPYF VRYQNLRLVR IHIFSDQCLF LDGIQSLWRG DACRLGSLTD WQKVHCVCDT
QLSNKSPSDH IASGAVLFNI RFLAARVLVT PNTVDLGHAL IANIPKNLVT LLTVLFIFVI
YFLLSICAIR KDIADSNRRD KIIFLSDNDP FDKVSYLVTL YTGSRWGAGT TADVFLQLIG
QNGTSDVHCL QHHYFTSFQQ GSSDCFLLTT KEDLGNILFF KVWHNNKGSS PSWFLSRAKV
ENMRTRKSWF FMCRKWLSLH KGDRLLERTF SVTNPKTPLP RTECFLISLG NSLTQDHPWL
SILAHVLRSS FSRFQRLSSC LAILLLNLLT NIMFFNADKN EESPMHLRYL RSITIGIECV
LINTPVEIVI NALFKYYQRQ PPPLAVAQTE PMVNSTLLSG NHNNWKESSQ KISLSDTSAQ
SVNTSPLEKL PGPLENLPGP SNSQIPPSEA RQKQPLPNSS FSTNYAEEES NLQKEREQQS
ITSRPFSKRP RVAFRRWCIY VAWTLVIAVT VLSAFFIVLY GLSYGYQTSV EWLLASITSF
IENVFFLSVL KIIFFSAIRT IRPISCENLE WFTWGEHSEI KLAKGMMNAE EMREKHLKLA
KVRGTKQYKP VEADEIAHML KIEKIKGKAL IFTTDFLSHL VFLTLLLKFA YSTDIANTFH
YSRFIHNQFS PQLSRIDKLE QIYVWVRDLF LPVIHNDIEP TFLPESRSKI IGLPRMRQVR
AKGTEKTCFH PHSFVNNSVI SKSHCLHKYG TDIPEKADYT GTWTKVANQS VSEHASSYSG
FAYQRNRTPW MHYSYGQLHT YGPEGYTFYF FPEEGRPNST TRLDALRQSK WLDEKTWAVI
IELTTFNPDA DLFCTISVIF EMSHLGIIKP RLSVHSFALP IFHLQTKTQM FVSVTVLAFL
LIYIAHELCI IGQEKKVYIK SISNIVSFSL KSALLPFVFL KAIKFKVGAD IVKFYLLHPN
DFIPFHAVSH LDQSLKITMG FLAFLAVLKT LRYSQLLYDV RLAQRSILAA LPGIASMTLV
VVVYYFAFMA FGYLVFGQHE WNYNSMIHSA QTIFSYCVSA FRDTTFSSNR LLGGLFLASF
TLVTVCILII LFQAIIMSAY GDMKQPIYEE PPDEAQMVAF VLQRLRRIFC FLICKKPKKS
ETDHFHTAVG TQPGRRYQRH LGLKNRKING KKMVYLV
//
