ID A0A091NHB4_9PASS Unreviewed; 687 AA.
AC A0A091NHB4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Metabotropic glutamate receptor 1 {ECO:0000313|EMBL:KFP78138.1};
DE Flags: Fragment;
GN ORFNames=N310_10960 {ECO:0000313|EMBL:KFP78138.1};
OS Acanthisitta chloris (rifleman).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Acanthisittidae;
OC Acanthisitta.
OX NCBI_TaxID=57068 {ECO:0000313|EMBL:KFP78138.1, ECO:0000313|Proteomes:UP000053537};
RN [1] {ECO:0000313|EMBL:KFP78138.1, ECO:0000313|Proteomes:UP000053537}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N310 {ECO:0000313|EMBL:KFP78138.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK833276; KFP78138.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091NHB4; -.
DR Proteomes; UP000053537; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:UniProt.
DR GO; GO:0007216; P:G protein-coupled glutamate receptor signaling pathway; IEA:UniProt.
DR GO; GO:0007200; P:phospholipase C-activating G protein-coupled receptor signaling pathway; IEA:UniProt.
DR CDD; cd15449; 7tmC_mGluR1; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR001256; GPCR_3_mGluR1.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR019588; Metabotropic_Glu_rcpt_Homer-bd.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF29; METABOTROPIC GLUTAMATE RECEPTOR 1; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF10606; GluR_Homer-bdg; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01051; MTABOTROPC1R.
DR PRINTS; PR00593; MTABOTROPICR.
DR SMART; SM01229; GluR_Homer-bdg; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFP78138.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053537};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 119..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..379
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 403..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..581
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP78138.1"
FT NON_TER 687
FT /evidence="ECO:0000313|EMBL:KFP78138.1"
SQ SEQUENCE 687 AA; 76119 MW; 2EE43EEBD23F25AF CRC64;
PCRYDIMNLQ YIEPNHYDYV LIGTWHEGVL NIDDYRIQMN KSGMVRSVCS EPCLKGQIKV
IRKGEVSCCW ICTACKENEF VQDEFTCKAC ELGWWPNADL TGCEPITVKY LQWSNIESIV
AVVFSCLGIL VTMFVTLIFV LYRDTPVVKS SSRELCYIIL AGIFLGYVCP FTLIAKPTTT
SCYLQRLLVG LSSAMCYSAL VTKTNRIARI LAGSKKKICT RKPRFMSAWA QVVIASILIS
VQLTLVITLI ILEPPMPILS YPSIKEVYLI CNTSNLGVVA PVGYNGLLIM SCTYYAFKTR
NVPANFNEAK YIAFTMYTTC IIWLAFVPIY FGSNYKIITT CFAVSLSVTV ALGCMFTPKM
YIIIAKPERN VRSAFTTSDV VRMHVGDGKA PCKSNTFLNI FRRKKPGAGN PNSNGKSVSW
SEPGGRQDPK GEHTWHRLSV HVKNQDTGCN QTAVIKPLTK DYQGQSLTFT DISSKTLYNV
VEEEDREPIH LNQSSSPSMV VHRRVTTTPP LQATAEETQL FLPEQSPKTL PLQPQSLMDQ
LEGVVNKFAP GIPDFNAVLP TPGSGNGVRP PYQPPTPPTL QPLQLAAFSQ EPLSSPAEEA
ESEKVKLIQG YVYEKNTEEE EDEEPATSKL TLEDSPALTP PSPFRDSVAS GSSVPSSPVS
ESVLCTPPDV TYASVILRDY KQSSSTL
//
