ID A0A091NLX8_APAVI Unreviewed; 524 AA.
AC A0A091NLX8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 42.
DE SubName: Full=Disintegrin and metalloproteinase domain-containing protein 12 {ECO:0000313|EMBL:KFP90758.1};
DE Flags: Fragment;
GN ORFNames=N311_04769 {ECO:0000313|EMBL:KFP90758.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP90758.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP90758.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP90758.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL388516; KFP90758.1; -; Genomic_DNA.
DR RefSeq; XP_009871579.1; XM_009873277.1.
DR AlphaFoldDB; A0A091NLX8; -.
DR MEROPS; M12.212; -.
DR GeneID; 104276828; -.
DR KEGG; avit:104276828; -.
DR CTD; 8038; -.
DR OrthoDB; 5406290at2759; -.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 4.10.70.10; Disintegrin domain; 1.
DR InterPro; IPR006586; ADAM_Cys-rich.
DR InterPro; IPR018358; Disintegrin_CS.
DR InterPro; IPR001762; Disintegrin_dom.
DR InterPro; IPR036436; Disintegrin_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR PANTHER; PTHR11905:SF112; DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF08516; ADAM_CR; 1.
DR Pfam; PF00200; Disintegrin; 1.
DR PRINTS; PR00289; DISINTEGRIN.
DR SMART; SM00608; ACR; 1.
DR SMART; SM00050; DISIN; 1.
DR SUPFAM; SSF57552; Blood coagulation inhibitor (disintegrin); 1.
DR PROSITE; PS00427; DISINTEGRIN_1; 1.
DR PROSITE; PS50214; DISINTEGRIN_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Integrin {ECO:0000313|EMBL:KFP90758.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 324..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..125
FT /note="Disintegrin"
FT /evidence="ECO:0000259|PROSITE:PS50214"
FT DOMAIN 271..303
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 365..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..446
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 97..117
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00068"
FT DISULFID 275..285
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 293..302
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP90758.1"
FT NON_TER 524
FT /evidence="ECO:0000313|EMBL:KFP90758.1"
SQ SEQUENCE 524 AA; 56512 MW; F34F04421A5F493A CRC64;
YPFPMVFSSC SRKDLENSLE KGVGMCLFNL PEVKESFGGQ KCGNGYVEDG EECDCGEPDE
CTNRCCNATT CALKPGAVCA HGLCCEDCQL KPAGISCRES SNSCDLPEFC TGASPHCPAN
VYLHDGHGCH GGDGYCYNGI CQTHEQQCIT LWGQGAKPAP GICFERVNSA GDPYGNCGKD
SKSSFAKCEP RDAKCGKIQC QGGASRPVIG TNAVSIETNI PLQEGGKILC RGTHVYLGDD
MPDPGLVLSG TKCEDGKICL NRRCQNTSVF GVHKCATKCH GRGVCNNKKN CHCEADWAPP
YCDKPGFGGS VDSGPIRQAD NKSLTVGVLI TILCLIFAGS IMYLKRKTFM KWLFTSKKTT
IEKLRSVTPA RPSSSSEPNP VHTTSLSKNL ILKPQNTNVQ KRDSPRRPLP YQIIDISNPV
KRHDLPQLKT PQRVLPPLPQ LPCHQAVPER PLPAHPSLRF AQENHKPNPP RKPLPADPLT
KARCNGAAAA APAHAKALPH VTPVRPAPKH PPQVSRSSNT ADVK
//
