ID A0A091P5R1_LEPDC Unreviewed; 344 AA.
AC A0A091P5R1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein RMD5 A {ECO:0000313|EMBL:KFQ02498.1};
DE Flags: Fragment;
GN ORFNames=N330_02709 {ECO:0000313|EMBL:KFQ02498.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ02498.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ02498.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ02498.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR EMBL; KK667903; KFQ02498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091P5R1; -.
DR PhylomeDB; A0A091P5R1; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16794; dRING_RMD5A; 1.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR045098; Fyv10_fam.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR037680; RMD5A_dRING.
DR InterPro; IPR044063; ZF_RING_GID.
DR InterPro; IPR027370; Znf-RING_euk.
DR PANTHER; PTHR12170:SF5; E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5A; 1.
DR PANTHER; PTHR12170; MACROPHAGE ERYTHROBLAST ATTACHER-RELATED; 1.
DR Pfam; PF10607; CTLH; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00757; CRA; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS51867; ZF_RING_GID; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01215}.
FT DOMAIN 106..163
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT DOMAIN 289..330
FT /note="RING-Gid-type"
FT /evidence="ECO:0000259|PROSITE:PS51867"
FT ZN_FING 289..330
FT /note="RING-Gid-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01215"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ02498.1"
FT NON_TER 344
FT /evidence="ECO:0000313|EMBL:KFQ02498.1"
SQ SEQUENCE 344 AA; 38658 MW; B7266589F17EAD4E CRC64;
DQDGDLSGTI SLVMTQCCKR IKDTVQKLAS DHKDIHSSVS RVGKAIDKNF DSDISSVGID
GCWQADSQRI LNEVMVEHFF RQGMLDVAEE LCQESGLSID QSQKEPFVEL NRILEALKVR
VLRPALEWAV SNREMLMAQN SSLEFKLHRL YFISLLMGGT ANQREALQYA KNFQPFALNH
QKDIQVLMGS LVYLRQGIEN SPYVHLLDAN QWADICDIFT RDACALLGLS VESPLSVSFS
AGCVALPALI NIKAVIEQRQ CTGVWNQKDE LPIEVDLGKK CWYHSIFACP ILRQQTTDNN
PPMKLVCGHI ISRDALNKMF NGSKLKCPYC PMEQSPGDAK QIFF
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