ID A0A091P7A0_APAVI Unreviewed; 1111 AA.
AC A0A091P7A0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Activating signal cointegrator 1 complex subunit 3 {ECO:0000256|ARBA:ARBA00014590};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
DE Flags: Fragment;
GN ORFNames=N311_05745 {ECO:0000313|EMBL:KFP87440.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP87440.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP87440.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP87440.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
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DR EMBL; KL381229; KFP87440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091P7A0; -.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17982; DEXHc_DHX37; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF99; ATP-DEPENDENT RNA HELICASE DHX37-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFP87440.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFP87440.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244}.
FT DOMAIN 222..389
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 419..671
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 28..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..145
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..535
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFP87440.1"
FT NON_TER 1111
FT /evidence="ECO:0000313|EMBL:KFP87440.1"
SQ SEQUENCE 1111 AA; 124309 MW; 248302D9B9E957B5 CRC64;
LSDEATLKGI DASNALVLPA KKAKKKRVPC VVQQQKKPLS KKQKKHLQKV LEQKEKKKQR
AELLSKLNEV QASEAEMKLL YTTSKLGIGE RMYQTKRVIH EPGTAVPEKI RSISGANKRR
HSSGSESEPE EEPSISEEEK EEQEQETENS SGGDLNTAAK PEEGVRAAAA NQQPAGPSAP
VCQPAANKPP CKPAVFIPVD RSPEIQEARL KLPILAEEQV IMEAIGENPI VIICGETGSG
KTTQVPQFLY EAGYASSDGA IGITEPRRVA AVSMSQRVAK EMNLSHRVVS YQIRYEGNVT
DETQIKFMTD GVLLKEIQKD FLLSKYKVVI IDEAHERSMY TDILIGLLSR IVPLREKKGL
PLKLIVMSAT LRVEDFTDNK RLFSVLPPVI QVDARQFPVT VHFNKKTPLD DYSGECFRKV
CKIHRMLPSG GILVFLTGQA EVHSLCRRLR KAFPFRKNDT AGGDDDKEES VEEIRKFKKS
RKRRKVMALP RIDLDNYSVV PVDEGDEDRD AETDDDIAGS DIDLDLGDGD SEEDEKSDSS
LPLYVLPLYS LLAPEKQAKV FRTPPPGTRL CVVATNVAET SLTIPGIKYV VDCGKVKKRF
YDKITGVSSF RVTWISQASA DQRAGRAGRT EPGHCYRLYS SAVFMDFEKF SAPEITKRPV
EDLILQMKAL NIEKVINFPF PTPPPAEALA AAEELLIALG ALKEPPMTGR LKQQLAAKLS
CPITPLGRIM ATFPVAPRYA KMLALSRQHD CLPYTITIVS ALTVRELFEE FDRRVISEEE
TAKLKGKRAK LLQMQRIWAG QGPMQKLGDL MVMLGAVGAC EYAGCTRTFC EENGLRYKAM
LEIRRLRGQL TTAVNSLCSD AGLYVDPKMK PPTEAQATYL RQIVLAGLGD HLARRVQAED
LLDDKWKNAY KTALLEDPVF IHPSSVLFKQ LPEFVVYQEI VETTKLYMKG VSAVEPEWIP
ALLPPYCHFG KPLESPPPSY CPETGRVRCH RPSVFYRVSW PLPAVEVDYP EGIDRYKYFA
RFLLEGKVIE KLSSYSRYLL SSPLIMLKTW AKLQARTESL LQALVGENCD NRDALLAAWR
KNPKFLLPAY CQWIPEAMHD DLAAKWPPVA L
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