ID A0A091P7X8_LEPDC Unreviewed; 1153 AA.
AC A0A091P7X8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|EMBL:KFQ03720.1};
DE Flags: Fragment;
GN ORFNames=N330_02902 {ECO:0000313|EMBL:KFQ03720.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ03720.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ03720.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ03720.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK669327; KFQ03720.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091P7X8; -.
DR PhylomeDB; A0A091P7X8; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR010526; Na_trans_assoc_dom.
DR InterPro; IPR024583; Na_trans_cytopl.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF278; SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 2.
DR Pfam; PF06512; Na_trans_assoc; 1.
DR Pfam; PF11933; Na_trans_cytopl; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000313|EMBL:KFQ03720.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..795
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 807..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..869
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 980..1003
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 140..442
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 566..729
FT /note="Voltage-gated Na+ ion channel cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF11933"
FT DOMAIN 779..1010
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1017..1152
FT /note="Sodium ion transport-associated"
FT /evidence="ECO:0000259|Pfam:PF06512"
FT REGION 28..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 432..477
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 28..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1153
FT /evidence="ECO:0000313|EMBL:KFQ03720.1"
SQ SEQUENCE 1153 AA; 130192 MW; 2A6B753F618F5E46 CRC64;
MAQSVLVPPG PDSFRYFTRE SLAAIEQRVN EEKAKKSKQE RKDDDDEDGP KPNSDLEAGK
TLPFIYGDIP PGMVSEPLED LDPYYINKKT FIVLNKGKAI FRFSATSALY MLTPFNPLRK
IAIKILVHSY PFQVVSLKPM LIMCTILTNC VFMTMSNPPD WTKNVEYTFT GIYTFESLIK
ILARGFCLED FTFLRDPWNW LDFTVITFAY VTEFVDLGNV SALRTFRVLR ALKTISVIPG
LKTIVGALIQ SVKKLSDVMI LTVFCLSVFA LIGLQLFMGN LRNKCLQWPP DNSTFETTVI
SYFNSSIGEN GTFINATMTT FNWDEYIEDR NHFYFLEGQN DALLCGNSSD AGQCPEGYIC
VKAGRNPNYG YTSFDTFSWA FLSLFRLMTQ DFWENLYQLT LRAAGKTYMI FFVLVIFLGS
FYLINLILAV VAMAYEEQNQ ATMEEAEQKE AEFQQMLEQL KKQQEEAQAA AAAAAADSRD
YSGVGGIGGF SETSSEASKL SSKSAKERRN RRKKKKQKEQ SEGEEKAGEE FHKSESEDSI
KKKGFRFSIE GNRLTYEKRF SSPHQSLLSI RGSLFSPRRN SRTSLFSFRG RAKDVGSEND
FADDEHSTFE DNESRRDSLF VPHRHGERRN SNISQASRSS RTVPPLPANG KMHSTVDCNG
VVSLVGGPPA LTSPTGQLLP EVMIDKAATA SNGTTTETDL RKRRSSSYHV PMDYLTDPSA
RQRAMSIASM LTNTMEELEE SRQKCPPCWY KFANTCLIWD CCTPWLKVKH IVNLIVMDPF
VDLAITICIV LNTLFMAMEH YPMTEQFSGV LSVGNLVFTG IFTAEMFLKI IAMDPYYYFQ
EGWNIFDGFI VSLSLMELGL ANVEGLSVLR SFRLLRVFKL AKSWPTLNML IKIIGNSVGA
LGNLTLVLAI IVFIFAVVGM QLFGKSYKEC VCKISSDCEL PRWHMHDFFH SFLIVFRVLC
GEWIETMWDC MEVAGQTMCL TVFMMVMVIG NLVVLNLFLA LLLSSFSSDN LAATDDDNEM
NNLQIAVARI QKGIDYVKRK MREFIQKAFV RKQKVLDEIK PLEDLNNKKD SCISNHTIVE
IGKNLAYLKE GNGTTSGIGS SVEKYVVDES DYMSFINNPS LTVTVPIAVG ESDFENLNTE
EFSSESDLEE SKE
//
