ID A0A091P955_HALAL Unreviewed; 611 AA.
AC A0A091P955;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Neuropilin-1 {ECO:0000313|EMBL:KFQ03738.1};
DE Flags: Fragment;
GN ORFNames=N329_02400 {ECO:0000313|EMBL:KFQ03738.1};
OS Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Haliaeetus.
OX NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ03738.1, ECO:0000313|Proteomes:UP000054379};
RN [1] {ECO:0000313|EMBL:KFQ03738.1, ECO:0000313|Proteomes:UP000054379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ03738.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the neuropilin family.
CC {ECO:0000256|ARBA:ARBA00006078}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK654149; KFQ03738.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091P955; -.
DR Proteomes; UP000054379; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0120035; P:regulation of plasma membrane bounded cell projection organization; IEA:UniProt.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00057; FA58C; 2.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46806:SF4; NEUROPILIN-1; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01285; FA58C_1; 2.
DR PROSITE; PS01286; FA58C_2; 2.
DR PROSITE; PS50022; FA58C_3; 2.
DR PROSITE; PS50060; MAM_2; 1.
PE 3: Inferred from homology;
KW Angiogenesis {ECO:0000256|ARBA:ARBA00022657};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00022974};
KW Heparan sulfate {ECO:0000256|ARBA:ARBA00023207};
KW Heparin-binding {ECO:0000256|ARBA:ARBA00022674};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Proteoglycan {ECO:0000256|ARBA:ARBA00022974};
KW Reference proteome {ECO:0000313|Proteomes:UP000054379};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..59
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 65..183
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 193..342
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 349..501
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 566..611
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ03738.1"
FT NON_TER 611
FT /evidence="ECO:0000313|EMBL:KFQ03738.1"
SQ SEQUENCE 611 AA; 68594 MW; B250D6D7877FC7FD CRC64;
RYDYVEVIDG DNAEGRLWGK YCGKIAPPPL VSSGPYLFIK FVSDYETHGA GFSIRYEVFK
RGPECSRNFT ASSGVIKSPG FPEKYPNSLE CTYIIFAPKM SEIILEFESF ELEPDSNTPG
GAFCRYDRLE IWDGFPDVGP HIGRYCGQNN PGRVRSSTGI LSMVFYTDSA IAKEGFSANY
SVSQSSVSED FQCMEPLGME SGEIHSDQIT VSSQYSAIWS SERSRLNYPE NGWTPGEDSI
REWIQVDLGL LRFVSGIGTQ GAISKETKKE YYLKTYRVDV SSNGEDWITL KEGNKPVVFQ
GNSNPTEVVY RPFAKPVLTR FVRIRPVSWE NGVSLRFEVY GCKITDYPCS GMLGMVSGLI
PDSQITASTQ VDRNWIPENA RLITSRSGWA LPPTTHPYTN EWLQIDLGEE KKVRGIIVQG
GKHRENKVFM KKFKIGYSNN GSDWKMIMDS SKKKIKTFEG NTNYDTPELR TFEPVSTRFI
RVYPERATHG GLGLRMELLG CELEAPTAVP TVSEGKPVDE CDDDQANCHS GTGDDYQLTG
GTTVLNTEKP TVIDNTLQPE LPLYNFNCAF GWGSQKTLCH WEHDNQVDLK WAILTSKTGP
IQDHTGNHEF M
//
