ID A0A091PAJ3_APAVI Unreviewed; 2168 AA.
AC A0A091PAJ3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Protein unc-13 C {ECO:0000313|EMBL:KFP88555.1};
GN ORFNames=N311_12809 {ECO:0000313|EMBL:KFP88555.1};
OS Apaloderma vittatum (Bar-tailed trogon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Trogoniformes; Trogonidae; Apaloderma.
OX NCBI_TaxID=57397 {ECO:0000313|EMBL:KFP88555.1, ECO:0000313|Proteomes:UP000054244};
RN [1] {ECO:0000313|EMBL:KFP88555.1, ECO:0000313|Proteomes:UP000054244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N311 {ECO:0000313|EMBL:KFP88555.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL382866; KFP88555.1; -; Genomic_DNA.
DR Proteomes; UP000054244; Unassembled WGS sequence.
DR GO; GO:0098793; C:presynapse; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR CDD; cd20859; C1_Munc13-2-like; 1.
DR CDD; cd04027; C2B_Munc13; 1.
DR CDD; cd08395; C2C_Munc13; 1.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 1.20.58.1100; -; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.70.1820; L1 transposable element, RRM domain; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR027080; Unc-13.
DR InterPro; IPR037302; Unc-13_C2B.
DR PANTHER; PTHR10480; PROTEIN UNC-13 HOMOLOG; 1.
DR PANTHER; PTHR10480:SF2; PROTEIN UNC-13 HOMOLOG C; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF06292; MUN; 1.
DR PRINTS; PR00360; C2DOMAIN.
DR SMART; SM00109; C1; 1.
DR SMART; SM00239; C2; 2.
DR SMART; SM01145; DUF1041; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054244};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1053..1103
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 1159..1283
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1591..1734
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 1840..1982
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT DOMAIN 1996..2123
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 26..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 253..287
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 41..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2168 AA; 246991 MW; 11E62113176D6697 CRC64;
MVSALLKSLI SPYIYKICKG MFTKKSGNST KRKESCQSKK EQDLTQIGQT KNPKFSNTLK
STVKKIAKCP SARNLSTEEE ESNREFSLSP TFSYRVAIAN GLQKHIFVTN NNNEDIVHDL
SSNDSSCSES LSEVKNSSKK NEYLSHTMPV RRNRKSLSSL APSDGSSDGE RTLHTLKLGA
LRKLRKWKKS QECVSSDSEL STWKKTWGLR SKSLDRAGRH QKSNTLEPGF SSTGCISQTH
DVMEMIFKEL QGISQIETEL SELRGHVNAL KQSIDEISSS VEVVQNEIEQ LRTGFVQSRR
ETRDIHDYIK QIGHPGNKAS LRFLNVPEER LEKTESMVYK ILIDKMGFSE AQSTIKIEFA
QRLGQQRDCP NAKPRPILVY FESSQQRDLV LKKSYKLKGT GIGISTDLFS HDVRDKKERG
LPSSQTYESM DMKLLTVETK TKIHDWESPD SDKDLESDIN KNSYAKISKS ALQVKTNTTK
ASIESPNTED LNRTADDNTF SNRRNYGNQS PEFDNMEKQS QTYYSDVTPL WHLQNDFATP
KLSRSESDFS KLCQSYSEDF SENQYFSRTN GGSLLSSSDR ELWQRRQDDS TVWYSSSQEQ
TFVQDVQQYP EQNEVENTAA VDSGVSNGII CASGDRSHFS DSQLSLHDDL SPWKDWNHLK
QGADMGLDSS TQDVFVYDMS SLDSESQSQW TGQYDDYQET NSISSYQNQN RLPMMYRSQS
ELPSDDSEET APKSWHSRLS IDLSDKSFSF PKFGSTLQRA KSALEVVWNK STQSLSGYED
SGSSFMGRFR TLSQSTANES STTLDSDVYA EPYCYKAEYE EDLIEPPGEN ETDYVEVMEQ
VLAKLENRTN SSETSEQVQE YELGQPLYEA PYAVLPEEQY DTQFNGVVIE QILEVESDMA
ADTEVREDEN QNIPEMLTET PKKKRIRPSF KEAALKAYKK QMNELEEKIL AGDSGSVDEK
ARIVSGSSLD TSKLYAVQAF SAAGRGLYGI DSMPDLRRKK SFPIVRDVTL AARKSGISMA
MLIRTSINND DMKIHVFKKT LQALIYPISS TTPHNFEVWT ATTPTYCYEC EGLLWGIARQ
GMRCTECGVK CHEKCQDLLN ADCLQRAAEK SSKHGAEDKT QNIISAMKER MKIREKNRPE
VFEVIQEMFN ISKEDFVQYT KAAKQSVLDG TSKWSAKITI TVLCAQGLQA KDKTGSSDPY
VTVQVGKTKR RTKTIFGNLN PVWDEKFYFE CHNSTDRIKV RVWDEDDDIK SRVKQHFKKE
SDDFLGQTII EVRTLSGEMD VWYNLEKRTD KSAVSGAIRL KINVEIEGEE KVAPYHVQYT
CLHENLFHYL TEVKSNGVVK IPEVRGDEAW KVYFDDAAQE IVDEFAMRYG IEYIYQAMTH
FSCLSSKYMC PGVPAVMSTL LANINAFYAH TTAATNVSAS DRFAATNFGR EKFIKLLDQL
HNSLRIDLSK YRDNFPASNS ERLQDLKSTV DLLTSITFFR MKVLELQSPP RASTVVKDCV
RACLDSTYKY IFDNCYDLYS QLVDQSKKQE VPKEEQGPTT KNLDFWAQLI TLMVTIIDED
KTAYTPILNQ FPQELNMGKI SAEIMWTLFA QDMKYALEEH EKQRLCKSTD YMNLHFKVKW
FYNEYVRELS AFKDAVPEYS LWFEPFVIQW LDENEDVSME FLHGALERDK KDGFQQTSDH
ALFSCSVVDV FTQLNQSFEI IRKLECPNPE ALSHLMRRFA KTINKVLLQY AVIISNYFSS
YCDKDNVPCI LMNNIQQLRV QLEKMFESMG GKELDPEASA VLKELQMKLS NVLDELSVTY
GTSFQFIIED CVRQMSNELN QMRGNGNAAA NKNSAAIDAE IVLRPLMDFL DKTLSVSAKI
CEKTVLKRVL KELWKLVLNK IEKQIVLPPL TDQTGPQMIF SAAKDLGQLS KLKDHMIREE
ARSLTLRQCA IMEVALVTIK QYFHAGGSGL KKNFLEKSPD LQSLKYALSL YTQTTDALIK
KFIDTQKSQS QTTNNSVGEI SIQVDVSTHP GTGEHKVTVK VVALNNLNWQ TTAMFRPFVE
VFLLGPNLSD KKRKHGTKTK SNTWSPKYNE TFQFILSNED KPGAYELHLS VKDYCFARED
RIIGMAVLQL QNIAEKGSCA SWYPLLRNIS VDETGLTILR ILSQRTNDEV AKEFVRLKTE
TRSAEEMA
//
