ID   A0A091PD32_LEPDC        Unreviewed;       775 AA.
AC   A0A091PD32;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   03-MAY-2023, entry version 32.
DE   SubName: Full=Microprocessor complex subunit DGCR8 {ECO:0000313|EMBL:KFQ05271.1};
GN   ORFNames=N330_10340 {ECO:0000313|EMBL:KFQ05271.1};
OS   Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX   NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ05271.1, ECO:0000313|Proteomes:UP000053001};
RN   [1] {ECO:0000313|EMBL:KFQ05271.1, ECO:0000313|Proteomes:UP000053001}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ05271.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK671422; KFQ05271.1; -; Genomic_DNA.
DR   RefSeq; XP_009959988.1; XM_009961686.1.
DR   AlphaFoldDB; A0A091PD32; -.
DR   GeneID; 104354692; -.
DR   KEGG; ldi:104354692; -.
DR   CTD; 54487; -.
DR   OrthoDB; 5404886at2759; -.
DR   PhylomeDB; A0A091PD32; -.
DR   Proteomes; UP000053001; Unassembled WGS sequence.
DR   GO; GO:0070877; C:microprocessor complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0031053; P:primary miRNA processing; IEA:InterPro.
DR   CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR   CDD; cd19868; DSRM_DGCR8_rpt2; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 3.30.160.20; -; 2.
DR   Gene3D; 3.30.160.590; -; 1.
DR   InterPro; IPR040375; DGCR8.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR13482:SF3; MICROPROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR   PANTHER; PTHR13482; MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   SMART; SM00358; DSRM; 2.
DR   SMART; SM00456; WW; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          303..336
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          513..580
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          745..775
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..42
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..275
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  87331 MW;  CB60CF6DB71A5514 CRC64;
     MEKYENVPPL PKEPAREMNV ENHTCPPPLP PNEQPPPPPL QTSSDAEVMD VGSGGDGQSD
     TPAGDTHSIC RTQLLTKGSA CYKSRLIIDP NNSDQSPRTA RHAPSVRKFT PDLKLLKDVK
     ISVSFTESCK SKDRKVLYTG VEQDYKADTD FGINNVNGDL HACPFGGSNG KAVGVGGEND
     DKKDDENDID QEKRVEYAVL DELEDFTDNL MEIDEEGGGF TSKAIVQRDK VDEETLNYSY
     EDDFDNDVDA LLEEGLRAPK TRRLENEKYG GESDHQSDGE TSVQPMMTKI KTVLKSRGRP
     PTEPLPDGWI MTFHNSGIPV YLHRESRVVT WSRPYFLGTG SIRKHDPPLS SIPCLHYKKM
     KENEEREQNN DITPNGEVSP VKHLDKSSEL DCQTEEPDST AADSGPLDDK DPSGGDAAQG
     ALGQVKAKVE VCKDESVDLE DFRRYLEKRF DFEQVTVKKF RTWAERRQFN REMKRKQAES
     ERPILPANQK LITLSVQDAP TKKEFVINPN GKSEVCILHE YMQRVLKVRP VYNFFECENP
     SEPFGASVII DGVTYGAGTA SSKKLAKNKA ARATLEILIP DFVKQTSEEK PKDSEELEYF
     NHISIEDSRV YELTSKAGLL SPYQILHECL KRNHGMGDTS IKFEVIPGKN QKSEYVMTCG
     KHTVRGWCKN KRVGKQLASQ KILQLLHPHV KNWGSLLRMY GRENSKMVKQ ETSDKSVIEL
     QQYAKKNKPN LHILNKLQEE MKKLAQEREE TRKKPKMTIV ESAQPGSEPL CTVDV
//