ID A0A091PFR9_HALAL Unreviewed; 403 AA.
AC A0A091PFR9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000256|ARBA:ARBA00039299};
DE Flags: Fragment;
GN ORFNames=N329_02007 {ECO:0000313|EMBL:KFQ06752.1};
OS Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Haliaeetus.
OX NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ06752.1, ECO:0000313|Proteomes:UP000054379};
RN [1] {ECO:0000313|EMBL:KFQ06752.1, ECO:0000313|Proteomes:UP000054379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ06752.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasmic vesicle,
CC secretory vesicle membrane {ECO:0000256|ARBA:ARBA00004360}; Peripheral
CC membrane protein {ECO:0000256|ARBA:ARBA00004360}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004360}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KK658753; KFQ06752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091PFR9; -.
DR Proteomes; UP000054379; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd10574; EVH1_SPRED-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR023337; KBD.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041937; SPRE_EVH1.
DR InterPro; IPR007875; Sprouty.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR11202:SF11; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR11202; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF05210; Sprouty; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51488; KBD; 1.
DR PROSITE; PS51227; SPR; 1.
DR PROSITE; PS50229; WH1; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054379};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..113
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT DOMAIN 192..246
FT /note="KBD"
FT /evidence="ECO:0000259|PROSITE:PS51488"
FT REGION 118..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ06752.1"
FT NON_TER 403
FT /evidence="ECO:0000313|EMBL:KFQ06752.1"
SQ SEQUENCE 403 AA; 45933 MW; 92E053250D266C50 CRC64;
DSYIVRVKAV VMTRDDSSGG WLPQEGGGLS RVGVCKVTYP EGNGRSGFLI HGERQKDKLV
VLECFVKKDL VYTKANPTFH HWKVDNRKFG LTFQSPADAR AFDRGVRKAI EDLIEGSTTS
SSTLHNEAEV GDDDVFTNAT DSSSNSSQKR EQPVRSLASP ASCEHRRICT RGHLHDHYSS
DHYHLEQSVP RSYRHVNFPD DDEEIVRINP REKIWMTGYE DYRHAPARGK NFDPDDMDSY
VRFAKSEASK HEYTYPYVDN SDFDLGEDIK GAVIKTQPVK FKPRRKEDGE RSRCVYCRDM
FNHEENKRGQ CQDAPDRVKT CIHRVSCMWC ADTMLYHCMS DPEGDYTDPC SCDTSDEMFC
LRWMALIALS FIAPCMCCYL PLRACYHCGV MCRCCGGKHK AAG
//
