ID A0A091PGD0_HALAL Unreviewed; 716 AA.
AC A0A091PGD0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
DE Flags: Fragment;
GN ORFNames=N329_02156 {ECO:0000313|EMBL:KFQ06308.1};
OS Haliaeetus albicilla (White-tailed sea-eagle) (Falco albicilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae;
OC Accipitrinae; Haliaeetus.
OX NCBI_TaxID=8969 {ECO:0000313|EMBL:KFQ06308.1, ECO:0000313|Proteomes:UP000054379};
RN [1] {ECO:0000313|EMBL:KFQ06308.1, ECO:0000313|Proteomes:UP000054379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N329 {ECO:0000313|EMBL:KFQ06308.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR EMBL; KK658115; KFQ06308.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091PGD0; -.
DR Proteomes; UP000054379; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd17404; MFS_SLCO5_OATP5; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF142; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
DR PROSITE; PS51465; KAZAL_2; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000054379};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 68..90
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 177..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 221..242
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 310..336
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 348..370
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 525..549
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 561..582
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 613..637
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT DOMAIN 1..638
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 426..479
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT REGION 247..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..276
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ06308.1"
FT NON_TER 716
FT /evidence="ECO:0000313|EMBL:KFQ06308.1"
SQ SEQUENCE 716 AA; 78150 MW; F4DABC4D363DA6DD CRC64;
FFLVCMCFLT FIQSLMVSGY LSSVITTIER RYSLKSSESG LLVSCFDIGS LVVVVFISYF
GGRGRRPLWL AVGGFFIALG AALFSLPHFI SPPYQIQELN SSVSNEGLCV TGNGTAKEQW
DSPACVKDSG GNDHSLYVAL FICAQILIGM GSTPIYTLGP TYLDDNVKKE NASLYLAIMY
VMGALGPAAG YLLGGLLIGF YVDPRTTVYI DQSDPRFIGN WWSGFLLCAI AMLLVIFPMF
TFPKKLPPRH KKKKKKKKMN SDDVSSDDEV MKEKTNSKIQ ADSAVPASMG FGKNVKELPR
AAVRILSNMT FLFVSLSYTA ESAIVTAFIT FIPKFIESQF GIPASNASIY TGVIIVPSAG
VGIVLGGYII KKLKLGARES AKLAMICSGV SLLCFSTLFI VGCESINLGG INIPYTTGPT
LAMAHRNLTG SCNVNCGCKI HEYEPVCGSD GITYFNPCLA GCINGGNHST GVRNYTECAC
VQSRQVITPP TVGQRSQLRL VIVKTYLNEN GYAVSGKCDR TCNTLIPFLI FLFIVTLITA
CAQPSAIIVT LRSVEDGERP FALGMQFVLL RTLAYIPTPI YFGAVIDTTC MLWQQDCGIQ
GSCWEYDVTS FRFVYFGLAA ALKFVGFFFI FLAWYSIKCK EEQLQRQRWR ASPVNTVSEM
VGQAGPQQNY ARTRSCPTFS SRGDISVAQG MNCVAQTYPG PFSEAINSSN ENALEE
//
