ID A0A091PSL1_LEPDC Unreviewed; 1250 AA.
AC A0A091PSL1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Peroxisomal ATPase PEX1 {ECO:0000256|ARBA:ARBA00034532};
DE AltName: Full=Peroxin-1 {ECO:0000256|ARBA:ARBA00032509};
DE Flags: Fragment;
GN ORFNames=N330_04327 {ECO:0000313|EMBL:KFQ10243.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ10243.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ10243.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ10243.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00034440};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC Evidence={ECO:0000256|ARBA:ARBA00034440};
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914}.
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DR EMBL; KK677680; KFQ10243.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091PSL1; -.
DR PhylomeDB; A0A091PSL1; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007031; P:peroxisome organization; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd19526; RecA-like_PEX1_r2; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.10.330.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR029067; CDC48_domain_2-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015343; PEX1-N-lobe.
DR InterPro; IPR015342; PEX1-N_C-lobe.
DR PANTHER; PTHR23077; AAA-FAMILY ATPASE; 1.
DR PANTHER; PTHR23077:SF12; PEROXISOME BIOGENESIS FACTOR 1; 1.
DR Pfam; PF00004; AAA; 2.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF09262; PEX-1N; 1.
DR Pfam; PF09263; PEX-2N; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF54585; Cdc48 domain 2-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 558..708
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 840..976
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 304..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1132..1154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1229..1250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ10243.1"
FT NON_TER 1250
FT /evidence="ECO:0000313|EMBL:KFQ10243.1"
SQ SEQUENCE 1250 AA; 138878 MW; 06A350FEB47D3AA8 CRC64;
GQAVKVSCGH QPMFLSWMEI RHRGHQGENI AEMNRQLAEK LGITDGEQVF LEPCSHVSSC
QQVEVEPLSA DDWEILELHA SSLEKHLLDQ IRIVFPKAVF PVWIEQHTHV YIKIGTLMPA
ACYGRLEPCT ELLILPKTRE LEENITSMPS TESDILLKSF VKNKMEQEET VKDPFAKQPY
LKPGVLEHSK TDANMTFGSN VLPNIWNFIG SVFCHTSEQK QKTLSDKDGM STFKDKLLNL
IHMDSIFRVC QSQPPSVQNA STTHAFLKCN AIHVFPWNLE FIDMNPNPVV SYGKINELLS
PRRRHQEAKE NLPFEKQKHL TSTQDKNHSN SNSSQASSEG SVVQIVWNGF EDLKSVMEYG
HSGEALHVGR VWIPDGLRKK LHIKIHSTVR IKSVESIPKI PVSLTLQPTQ NLHKDIHEDD
VKSAFSSWLQ DFTSDDLPWI MTSTDYIHLS VKEGMEEFVL SAVHPVHIEA NTSENIFILS
PSLLQKTNMQ VLLHPLTRKA DNDSQPPMCD TDRNLPYYKL NDLGGVDKLG TSSFEHISHS
LLGRPLSQKL AAVAVGLRSG GVLLTGGKGS GKSTLAKAIC KEAFDRLDAH VEVIDCKALR
GKRLANIRKN VEEAFLEAAW RQPSILLMDD LDHIVGVPPT PEHENSPETV QSNRLAYVLK
DLIKEVISMG SLIALIATSQ SEHSLHPSLV SAQGTHIFQC FKCIRSPDQK QRCEMLYSII
KKKLNADIKK SSGLDLQCIA KETEGFVARD FTMLVDRAIH ACVSNQNAFQ NGELNLSTMD
FQKALKGFTP LALRNVKLHK PKDIGWDRIG GLKDVKQILM DTIMLPAKYP ELFANLPIRQ
RSGVLLYGAP GTGKTMLAGV VARESGMNFI SIKGPELLSK YIGASEQAVR DIFNRAQAAK
PCIVFFDEFD SVAPRRGHDN TGVTDRVVNQ LLTQLDGVEG LQGVYVLAAT SRPDLIDPAL
LRPGRLDKCL YCPPPDQNSR CEILEALSHS LSFANDVDFQ DLAAKTEQFT GADLKALLYN
AQLEAIRTNL GSGLTQDFGC SSDSDFSLSS MVFLNHSSGS DDSAIDGEAG LEQSLISLDM
SDLLPEDPRS NMYRLYFGSS YESELGNGTP SELSSLCLSG PNSITHDFTS VTQRDTASAQ
PSVLRTASPE DSLENNQEQQ IEHLRTEINA IKANYRSKNG DSTFNQSVLA KNTLIITQSH
LMTALDGIRP SISQGDWKNF TELYDNFQNP KKRKGQVGST FRPGQKITLA
//
