ID A0A091PWE5_LEPDC Unreviewed; 711 AA.
AC A0A091PWE5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 44.
DE SubName: Full=Disks large 1 {ECO:0000313|EMBL:KFQ12272.1};
DE Flags: Fragment;
GN ORFNames=N330_05111 {ECO:0000313|EMBL:KFQ12272.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ12272.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ12272.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ12272.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK680139; KFQ12272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091PWE5; -.
DR PhylomeDB; A0A091PWE5; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0031594; C:neuromuscular junction; IEA:InterPro.
DR GO; GO:0043005; C:neuron projection; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR CDD; cd12031; SH3_DLG1; 1.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019583; DLG1-4_PDZ_assoc.
DR InterPro; IPR016313; DLG1-like.
DR InterPro; IPR019590; DLG1_PEST_dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF5; DISKS LARGE HOMOLOG 1; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF10608; MAGUK_N_PEST; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF10600; PDZ_assoc; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PIRSF; PIRSF001741; MAGUK_DLGH; 3.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM01277; MAGUK_N_PEST; 1.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 52..139
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 147..234
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 296..377
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 411..481
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 521..696
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ12272.1"
FT NON_TER 711
FT /evidence="ECO:0000313|EMBL:KFQ12272.1"
SQ SEQUENCE 711 AA; 78924 MW; B198FEB0D9BF2534 CRC64;
KYRYQDEDTP PQEHSSPHIT NEANPPPVLV NTDSLETPTY VNGTDADYEY EEITLERGNS
GLGFSIAGGT DNPHIGDDSS IFITKIIAGG AAAQDGRLRV NDCILRVNEV DVRDVTHSKA
VEALKEAGSI VRLYVKRRKP VTEKIVEIKL VKGPKGLGFS IAGGVGNQHI PGDNSIYVTK
IIEGGAAHKD GKLQIGDKLL AVNSVCLEEV THEEAVTALK NTSDFVYLKV AKPTSMFMND
SYAPPDITNS YSQPVDNHIT QSAYLGQSLP PASPGRYSPI PKGVLGDDEI TREPRKVILH
RGSTGLGFNI VGGEDGEGIF ISFILAGGPA DLSGELRKGD RIISVNGVDL KAATHEQAAA
ALKNAGQAVT IVAQYRPEEY SRFEAKIHDL REQMMNSSIS SGSGSLRTSQ KRSLYVRALF
DYDKTKDSGL PSQGLNFKFG DILHVINASD DEWWQARQVT PDGESDEIGV IPSKRRVEKK
ERARLKTVKF NSKTRGDKGV SGQEEYVLSY EPVNQQEVSY TRPVIVLGPM KDRINDDLIS
EFPDKFGSCV PHTTRPKRDY EVDGRDYHFV TSREQMEKDI QDHKFIEAGQ YNNHLYGTSV
QSVREVAEKG KHCILDVSGN AIKRLQIAQL YPISIFIKPK TVENIMEMNK RLTEEQARKT
FERAMKLEQE FTEHFTAIVQ GDTLEEIYNQ VKQIIEEQSG PYIWVPAKEK L
//
