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Database: UniProt
Entry: A0A091Q8Z7_MERNU
LinkDB: A0A091Q8Z7_MERNU
Original site: A0A091Q8Z7_MERNU 
ID   A0A091Q8Z7_MERNU        Unreviewed;      1505 AA.
AC   A0A091Q8Z7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   11-DEC-2019, entry version 23.
DE   SubName: Full=Rho GTPase-activating protein 5 {ECO:0000313|EMBL:KFQ21609.1};
GN   ORFNames=N331_01755 {ECO:0000313|EMBL:KFQ21609.1};
OS   Merops nubicus (Northern carmine bee-eater).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX   NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ21609.1, ECO:0000313|Proteomes:UP000052967};
RN   [1] {ECO:0000313|EMBL:KFQ21609.1, ECO:0000313|Proteomes:UP000052967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ21609.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK691216; KFQ21609.1; -; Genomic_DNA.
DR   RefSeq; XP_008934628.1; XM_008936380.1.
DR   GeneID; 103769167; -.
DR   CTD; 394; -.
DR   OrthoDB; 110157at2759; -.
DR   Proteomes; UP000052967; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 3.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF01846; FF; 1.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00441; FF; 4.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF81698; SSF81698; 1.
DR   PROSITE; PS51676; FF; 4.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          267..325
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          366..420
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          427..481
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          482..548
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          590..763
FT                   /note="PG1 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51852"
FT   DOMAIN          779..944
FT                   /note="PG2 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51853"
FT   DOMAIN          1264..1451
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          948..1003
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1068..1090
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1134..1158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1170..1256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          309..329
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1170..1201
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1234..1250
FT                   /note="Basic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1505 AA;  172112 MW;  6899A0294ADF0774 CRC64;
     MMAKNKEPRP PSYAVSVVGL SGTEKDKGNC GVGKSCLCNR FVRSKADEYY PEHTSVLSTI
     DFGGRVVNND HFLYWGDVTQ SGEDGIECRI HVIEQTEFID DQTFLPHRST NLQPYIKRAA
     ASKLQSAEKL MYICTDQLGL EQDFEQKQMP EGKLSIDGFL LCIDVSQGCN RKFDDQLKFV
     NNLYIQLSKS KKPIIIAATK CDECVDHYLR EVQAFASNKK NLVVVETSAR FNVNVETCFT
     ALVQMMDKTR GKPKIIPYLD AYKTQRQLVV TATDKFEKLV QTVRDYHATW KTVSNKLKNH
     PDYEEYINLE GTKKARNTFS KHIEQLKQEH IRKRKEEYIN ALPRALNTLL SNLDEVEHLT
     WAEALKLMEK RPDFQSCFVV LEKTPWDETD HIDKVNDRRI PFDLLTTLEA EKVYQNHVQH
     LISEKRRVEM KEKFKKTLDK IQFISPGQPW EEVICFVVDD EAFKYITDAD SKEVYGRHQR
     EIVEKAKEEF QEMLFEHSEL FYDLDLNATP SSDKMSEIHA VLSEEPRYKA LQKLAPDRES
     LLLKHIGFVY HPTKETCLSG QNCTDIKVEQ LLANSLLQLD HGRSNLYHDS ANIDKVNLFI
     LGKDGLAQEL ANEIRTQSTD DEYALDGKIY ELDLRPVDAK SPYLLTQFWT STFKPHGCFC
     VFNSIESLNF IGECIAKIRA EASQIRRDKY MANLPFTLIL ANQRDSVSKN LPILRHQGQQ
     LANKLQCPFV DVPAGTYPRK FNETQIKQAL RGVLEAVKHN FDVVSPVPTI KDLSEADLRI
     VMCAMCGDPF SVDLILSPFL DSHSCSAAQA GQNNSLMLDK IIGEKRRRIQ ITILSYHSSI
     GVRKDELVHG YILVYSAKRK ASMGMLRAFL SEVQDTIPVQ LVAVTDSQAD FFENEAIKEL
     MTEGEHIATE ITAKFTALYS LSQYHRQTEV FTLFFSDVLE KKSMIESSYM SDSTRETTHT
     SEDVFPRSPR GSSLDYNYPD SEDDTEGPPP YSPIGDDVRL LPAPSDRSKY RLDLEGNEYP
     IHSTPLNCHD HERNHKVPPP IKPKPLVPRA NVKKLDPNLL KTIEAGIGKN PRKQPSRVPV
     APPEDVDQSD NYAEPLDTIF KHKGFADDIY AVPEDSQNRI IKVRNSVVIN TQGEEENGFT
     DRMSKSHGER RPSKYKYKSK TLFSKAKSYY RRTHSDASDD EAFTTSKTKR KGRHRGSEED
     PLLSPVETWK GGIDNPAITS DQELDDKKMR KKTQKVKEDK KLKKKTKPLN PPIRRNWESN
     YFGMPLQDLV TPEKPIPLFV EKCVQFIEDT GLCTEGLYRV SGNKTDQDNI QKQFDQDHNI
     SLEAMGVTVN AVAGALKAFF ADLPDPLIPY SLHQELLETS KIMDKTERLH ELKEIVKKFH
     PVNYDVFKYV ITHLNRVSQQ YKTNFMTADN LSICFWPTLM RPDFENREFL STTKIHQSVI
     ETFIQQCQFF FYNGEIVEAP NPVASQPPPS NAVQMVEPMV PLQLPPPLQP QLIQSQLPAD
     PLGII
//
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