ID   A0A091QME8_MERNU        Unreviewed;       274 AA.
AC   A0A091QME8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 28.
DE   RecName: Full=F-actin-capping protein subunit alpha {ECO:0000256|RuleBase:RU365077};
DE   Flags: Fragment;
GN   ORFNames=N331_02906 {ECO:0000313|EMBL:KFQ28114.1};
OS   Merops nubicus (Northern carmine bee-eater).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX   NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ28114.1, ECO:0000313|Proteomes:UP000052967};
RN   [1] {ECO:0000313|EMBL:KFQ28114.1, ECO:0000313|Proteomes:UP000052967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ28114.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: F-actin-capping proteins bind in a Ca(2+)-independent manner
CC       to the fast growing ends of actin filaments (barbed end) thereby
CC       blocking the exchange of subunits at these ends. Unlike other capping
CC       proteins (such as gelsolin and severin), these proteins do not sever
CC       actin filaments. {ECO:0000256|RuleBase:RU365077}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta subunit.
CC       {ECO:0000256|RuleBase:RU365077}.
CC   -!- SIMILARITY: Belongs to the F-actin-capping protein alpha subunit
CC       family. {ECO:0000256|ARBA:ARBA00010479, ECO:0000256|RuleBase:RU365077}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK702392; KFQ28114.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091QME8; -.
DR   Proteomes; UP000052967; Unassembled WGS sequence.
DR   GO; GO:0008290; C:F-actin capping protein complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1140.60; F-actin capping protein, alpha subunit; 1.
DR   Gene3D; 3.90.1150.210; F-actin capping protein, beta subunit; 1.
DR   InterPro; IPR002189; CapZ_alpha.
DR   InterPro; IPR037282; CapZ_alpha/beta.
DR   InterPro; IPR042276; CapZ_alpha/beta_2.
DR   InterPro; IPR042489; CapZ_alpha_1.
DR   InterPro; IPR017865; F-actin_cap_asu_CS.
DR   PANTHER; PTHR10653; F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR10653:SF2; F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-2; 1.
DR   Pfam; PF01267; F-actin_cap_A; 1.
DR   PRINTS; PR00191; FACTINCAPA.
DR   SUPFAM; SSF90096; Subunits of heterodimeric actin filament capping protein Capz; 1.
DR   PROSITE; PS00748; F_ACTIN_CAPPING_A_1; 1.
DR   PROSITE; PS00749; F_ACTIN_CAPPING_A_2; 1.
PE   3: Inferred from homology;
KW   Actin capping {ECO:0000256|RuleBase:RU365077};
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203,
KW   ECO:0000256|RuleBase:RU365077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052967}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ28114.1"
FT   NON_TER         274
FT                   /evidence="ECO:0000313|EMBL:KFQ28114.1"
SQ   SEQUENCE   274 AA;  31468 MW;  08ABD5EB23F43CEF CRC64;
     KVRIAAKFII HAPPGEFNEV FNDVRLLLNN DNLLREGAAH AFAQYNLDQF TPVKIDGYDE
     QVLITEHGDL GNGKFLDPKN KISFKFDHLR KEATDPRPHE VENAIESWRN SVETAMKAYV
     KEHYPNGVCT VYGKTIDGQQ TIIACIESHQ FQAKNFWNGR WRSEWKFTIT PSTTQVAGIL
     KIQVHYYEDG NVQLVSHKDI QDSLTVSNEA QTAKEFIKIV EAAENEYQTA ISENYQTMSD
     TTFKALRRQL PVTRTKIDWN KILSYKIGKE MQNA
//