ID A0A091QSV6_MERNU Unreviewed; 624 AA.
AC A0A091QSV6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Plasma kallikrein {ECO:0000313|EMBL:KFQ29686.1};
DE Flags: Fragment;
GN ORFNames=N331_12157 {ECO:0000313|EMBL:KFQ29686.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ29686.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ29686.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ29686.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK705052; KFQ29686.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091QSV6; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd01100; APPLE_Factor_XI_like; 4.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 4.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR000177; Apple.
DR InterPro; IPR003609; Pan_app.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR PANTHER; PTHR24252:SF7; HYALIN; 1.
DR Pfam; PF00024; PAN_1; 4.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00005; APPLEDOMAIN.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00223; APPLE; 4.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50948; PAN; 3.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..624
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001880159"
FT DOMAIN 18..101
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 108..191
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 198..281
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT DOMAIN 390..624
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ29686.1"
FT NON_TER 624
FT /evidence="ECO:0000313|EMBL:KFQ29686.1"
SQ SEQUENCE 624 AA; 70765 MW; 766E9EE644A1488F CRC64;
VHALILIIYK FSYSVSECMT QIYENTYFQG GDLATVFTPS ANYCQIVCTY HPTCLLFTYL
PAAWTKDPAK RFSCYLKDSD TEMLPKVDME EAISGHSLKQ CDIQISACSP DVHIGLDMEG
KIYNVTMANS YQQCQKRCTN DKHCHFFTYA SETFHNASFR KKCFLKHTSV GTPTSITVLD
EVVSGFSLKP CQLSEIDCQT DIFKDQEFSG MNITSFFTPD VSVCQTICTY FPKCLFFTFF
TREWQIESQR NLCLLKTSAS GIPESLISQE NTISGFGLLN CRKPVPACSS RTYMHMNFLG
DELNVTYTKG HRACQQVCTD VIRCQFFTYF PLPDSCNEER KCECHLRMSS TGSPVEIVHG
PGRISGYSLR LCKKKASTVC MQHSAGTIRI VGGTDSSPGE WPWQVSLHVK LSRQRHLCGG
SIISKRWILT AAHCVMSLEN PNIWRVYAGI LKQSEINEDT PFFKVEEIIV HPQYKYAQTG
YDIALMKLDK PMNFTDLQLP ICLPSKEDTN ILYTDCWVIG WGYRKEKGRV EDILQKATVP
LMSKEECQAR YRKRRIGDKV ICAGYDEGGR DACKGDSGGP LSCRHEEVWY LVGITSWGEG
CARPRQPGVY TKVAEYSDWI LEKT
//
