ID A0A091QV46_LEPDC Unreviewed; 915 AA.
AC A0A091QV46;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|EMBL:KFQ13264.1};
DE Flags: Fragment;
GN ORFNames=N330_08416 {ECO:0000313|EMBL:KFQ13264.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ13264.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ13264.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ13264.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the BRAG family.
CC {ECO:0000256|ARBA:ARBA00006248}.
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DR EMBL; KK682671; KFQ13264.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091QV46; -.
DR PhylomeDB; A0A091QV46; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd13318; PH_IQSEC; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR033742; IQSEC_PH.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF327; IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF16453; IQ_SEC7_PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053001}.
FT DOMAIN 498..691
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ13264.1"
FT NON_TER 915
FT /evidence="ECO:0000313|EMBL:KFQ13264.1"
SQ SEQUENCE 915 AA; 103925 MW; 6DF78D7B9F79EFB3 CRC64;
SSVEGEAPSS ETGTSLDSPS AYHQGPITHS SAINPDHYDH SAYGLYSVSP GQQRSRRPKL
QHSTSILRKQ AEEEAIKRSR SLSESYELSS DLQDKQVEML ERKYGGRLIT RHAARTIQTA
FRQYQMNKNF ERLRSSMSEN RMSRRIVLSN MRMQFSFEGP EKVHSSYFEG KQVSVTNDES
KLGSMVPSEC GDLGEPATMK SPAASTDFAD AITELEDAFS RQVKSLAESI DDALNCRSLH
SDEVQTPDQV RSCEMERDSC PQTKPAIHSV DHRKLDEMTA SYSDVTLYID EEELSPPLPL
SQSVDRPSST ESDLRLRSMN SCQEYWSMTH KDDKVDTDTS CRSTPSLECQ EQRMRMDHLP
LLTIEPPSDS SVDLSDRSER GSLKRQNAYD RGITSQQGSP KHIPHSIPAK IISREEQEAR
HRARPIDSHL AINGTANRQS KSESDYSDGD NDSINSTSNS NDTINCSSES SSRDSLREQT
LSKQTYHKET RNSWDSPAFS NDVIRKRHYR IGLNLFNKKP EKGVQYLIER GFVPDTPVGV
AHFLLQRKGL SRQMIGEFLG NRQKQFNRDV LDCVVDEMDF STMELDEALR KFQAHIRVQG
EAQKVERLIE AFSQRYCICN PGVVRQFRNP DTIFILAFAI ILLNTDMYSP NVKPERKMKL
EDFVKNLRGV DDGEDIPREM LIGIYERIRK RELKTNEDHV SQVQKVEKLI VGKKPIGSLH
HGLGCVLSLP HRRLVCYCRL FEVPDPNKPQ KLGLHQREIF LFNDLLVVTK IFQKKKNSVT
YSFRQSFSLY GMQVLLFENQ YYPNGIRLTS AVPGADIKVL INFNAPNPQD RKKFTDDLRE
SIAEVQEMEK HRIESELEKQ KGVVRPSMSQ CSSLKKDSGN GTLNRACLDD SYATGEGLKR
SALSSSLRDL SEAGK
//
