ID A0A091QW29_MERNU Unreviewed; 533 AA.
AC A0A091QW29;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Neutral amino acid transporter 9 {ECO:0000256|ARBA:ARBA00040233};
DE AltName: Full=Solute carrier family 38 member 9 {ECO:0000256|ARBA:ARBA00042870};
GN ORFNames=N331_06052 {ECO:0000313|EMBL:KFQ30811.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ30811.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ30811.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ30811.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-asparagine(out) = L-asparagine(in); Xref=Rhea:RHEA:73423,
CC ChEBI:CHEBI:58048; Evidence={ECO:0000256|ARBA:ARBA00036663};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutamine(out) = L-glutamine(in); Xref=Rhea:RHEA:73419,
CC ChEBI:CHEBI:58359; Evidence={ECO:0000256|ARBA:ARBA00036878};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-leucine(in) = L-leucine(out); Xref=Rhea:RHEA:73011,
CC ChEBI:CHEBI:57427; Evidence={ECO:0000256|ARBA:ARBA00036887};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-tyrosine(in) = L-tyrosine(out); Xref=Rhea:RHEA:68572,
CC ChEBI:CHEBI:58315; Evidence={ECO:0000256|ARBA:ARBA00036984};
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC SLC38A9 subfamily. {ECO:0000256|ARBA:ARBA00038442}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK706751; KFQ30811.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091QW29; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF244; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 9; 1.
DR Pfam; PF01490; Aa_trans; 2.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..206
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT DOMAIN 267..529
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
SQ SEQUENCE 533 AA; 59918 MW; 597F26B611B75EF9 CRC64;
MNIQFDPEDF KCKRPFHVEP TNIVSVNDDM QRVTDEAAAM NKRIHYYSRL TSPADRALIA
PDHVLPAPDE IYVYSPLGTA FKVDSCTDGH GKNSSVVTIF MIWNTMMGTS ILSIPWGIKQ
AGFTFGIILI LLMGILTLYC CYRVVKSRKT IPLIDTSNWE FPDVCKYYFG PFGQWSSLLF
SMISLVGAMV VYWVLMSNCL FNTGKFIYNF VHDINVTDIV PGTNGSNKVI CPSAASGLPP
QNSSVMFSSG NDTGFELFER WWNKSQTVPF YLIAVLLPLL NLKSPSFFAK FNVLGTVSVV
YLVFLVTVKA ARLGIHLEYN WFTENDFFVP EFRILFPQLT GVLTLAFFIH NCVITLLQNN
RNQENNVRDL SIAYFLVGLT YLYVGAIIFA SFPSPPLSKE CIEQNFLDNF PSDDIMSFVA
RIFLPVYPLL GYLARVQLLR QFFGNPYPSV LHVLVLNIAI VGAGVAMARF YPNIGGIIRY
SGATCGLAFV FVYPSFIYVI SLHRAGQLTW PALIIHIFII LLGLANLIAQ FLL
//
