ID A0A091R046_LEPDC Unreviewed; 481 AA.
AC A0A091R046;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=GPI ethanolamine phosphate transferase 2 {ECO:0000256|ARBA:ARBA00020830};
DE Flags: Fragment;
GN ORFNames=N330_07629 {ECO:0000313|EMBL:KFQ14989.1};
OS Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus.
OX NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ14989.1, ECO:0000313|Proteomes:UP000053001};
RN [1] {ECO:0000313|EMBL:KFQ14989.1, ECO:0000313|Proteomes:UP000053001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ14989.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
CC {ECO:0000256|ARBA:ARBA00005315}.
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DR EMBL; KK687036; KFQ14989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091R046; -.
DR PhylomeDB; A0A091R046; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000053001; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16024; GPI_EPT_2; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR037674; PIG-G_N.
DR InterPro; IPR039527; PIGG/GPI7.
DR PANTHER; PTHR23072:SF0; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2; 1.
DR PANTHER; PTHR23072; PHOSPHATIDYLINOSITOL GLYCAN-RELATED; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW Transferase {ECO:0000313|EMBL:KFQ14989.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ14989.1"
FT NON_TER 481
FT /evidence="ECO:0000313|EMBL:KFQ14989.1"
SQ SEQUENCE 481 AA; 53420 MW; 83A4FC39385CCB13 CRC64;
SNWTKIPPPV FKKVVIVLID ALRDDFVFGS KGKQFMPYTT QVVEKGTSHS FIAEVKPPTV
TMPRIKALMT GSIPGFIDVI VNLNSPALLD DNLIWQAKTA GKRIIFYGDD TWVKLFPKHF
VEYDGTTSFF VSDFTEVDDN VTRHLDSVLK REDWDLLILH YLGLDHIGHM TGPNSPLVGP
KLREMDNILK KIHISLLSKE ETSLPNLLVV CGDHGMSETG SHGGSSEGEV HTPLLFISSA
FEKRSGPLTQ PELVQQTDLA STLAVGLGLP ISRNSVGNLI LPVVGGKTMR EQLRFVHLNG
FQLSRLLQEN TPAYEKDPGY EHFKIAEKSH GNWIKLWLEG NNSEILLNLG KKVLKQYLEA
LKTLSSSLSK QVAQYDLYSM MVGTVIIMEV LLLLLLSIPK ALSSQAEFEV PLSPPLFSLL
FYLMCLMLCA VHVIVCTSAE TLCYFCSMSW LTAVGVMMLI SALMCGILSA IPKIFENSRI
P
//
