ID A0A091R0E8_9GRUI Unreviewed; 730 AA.
AC A0A091R0E8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Leucine-rich repeat-containing G-protein coupled receptor 4 {ECO:0000313|EMBL:KFQ32674.1};
DE Flags: Fragment;
GN ORFNames=N332_13899 {ECO:0000313|EMBL:KFQ32674.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ32674.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ32674.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ32674.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK806787; KFQ32674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091R0E8; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
DR GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd15361; 7tmA_LGR4; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR002131; Gphrmn_rcpt_fam.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24372; GLYCOPROTEIN HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24372:SF67; LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR Pfam; PF13855; LRR_8; 4.
DR PRINTS; PR00373; GLYCHORMONER.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 12.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFQ32674.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 452..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 468..714
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ32674.1"
FT NON_TER 730
FT /evidence="ECO:0000313|EMBL:KFQ32674.1"
SQ SEQUENCE 730 AA; 81199 MW; 2227F2B92FFD618D CRC64;
RLAGNDLSFI HPKALSGLKE LKVLTLQNNQ LKTVPNEAIR GLSGLQSLRL DANHITAIPE
DSFEGLVQLR HLWLDDNSLT EVPIYPLSNL PSLQALTLAL NKITHIPNYA FTNLSSLVVL
HLHNNKIKTI GKHCFDGLDN LETLDLNYNN MVEFPEAIKA LPSLKELGFH SNYISIIPDG
AFAGNPLLRT IHLYDNPLSF VGSSAFQNLS DLHSLVIRGA SMVQWFPNLT GTVNLESLTL
TGTKIISIPV NLCQEQRVLR TLDLSYNIIK DLPSFKGCHS LEEISLQHNQ IHEIAEDTFQ
GLSSLRILDL SRNRIHQIHK EAFTTLGAIV NLDLSFNELT SIPTEGLSGL NQLKLAGNSE
LKEALAAKNF AKLRSLSVPY AYQCCAFWGC DSYLNSNAED SSHQDQGALM DREKADADVL
RNEENEELGQ TIIHCTPATG AFKPCEYLLG SWMIRLTVWF IFLVALFFNL LVLLTIFASC
TPLPSSKLFI GLISVSNLFM GVYTGILTFL DAVSWGRFAE FGIWWETGSG CRVAGFLAVF
SSESAIFFLM LAAVERSFSA KEIIKKGKSN RQKQFQVAAV FAFLCAVVAG CLPLFYKAEH
SASPLCLPFP TGETPSLGFT VTLVLLNSLA FLLMAIIYTK LYCNLEKEDL SENSQSSMIK
HVAWLIFTNC IFFCPVAFFS FAPLITAISI SPEIMKSVTL IFFPLPACLN PVLYVFFNPK
FKEDWKLLRR
//
