ID A0A091R4C0_MERNU Unreviewed; 1639 AA.
AC A0A091R4C0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|EMBL:KFQ34663.1};
DE Flags: Fragment;
GN ORFNames=N331_12354 {ECO:0000313|EMBL:KFQ34663.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ34663.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ34663.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ34663.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK713216; KFQ34663.1; -; Genomic_DNA.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR CDD; cd13433; Na_channel_gate; 1.
DR Gene3D; 1.10.287.70; -; 3.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 4.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR044564; Na_chnl_inactivation_gate.
DR InterPro; IPR010526; Na_trans_assoc_dom.
DR InterPro; IPR024583; Na_trans_cytopl.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF237; SODIUM CHANNEL PROTEIN TYPE 3 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR Pfam; PF06512; Na_trans_assoc; 1.
DR Pfam; PF11933; Na_trans_cytopl; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000313|EMBL:KFQ34663.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 798..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 878..906
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 968..991
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1219..1237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1258..1280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1286..1306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1335..1361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1459..1483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1550..1568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1580..1598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1610..1630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 133..438
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 565..717
FT /note="Voltage-gated Na+ ion channel cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF11933"
FT DOMAIN 767..998
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1005..1212
FT /note="Sodium ion transport-associated"
FT /evidence="ECO:0000259|Pfam:PF06512"
FT DOMAIN 1217..1491
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1549..1629
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 27..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1130..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 428..473
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 27..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1639
FT /evidence="ECO:0000313|EMBL:KFQ34663.1"
SQ SEQUENCE 1639 AA; 186321 MW; 3FE9EF076F3D3BC8 CRC64;
MAQALLVPPG PESFRYFTRD SLTAIEKRSA EEKAKKPKQE HTDDDDENGP KPNSDLEAGK
TLPFIYGDIP PGMVSEPLED LDPYYINKKT FIVLNKGKAI FRFSATSALY ILTPFNPIRK
IAIKILVHSY PFFLTMLIMC TILTNCVFMT MSNPPDWTKN VEYTFTGIYT FESLIKILAR
GFCLEGFTFL RDPWNWLDFS VILMAYVTEF VDLGNVSALR TFRVLRALKT ISVIPGLKTI
VGALIQSVKK LSDVMILTVF CLSVFALIGL QLFMGNLRNK CLQWPPDNST FEINIISYFN
STMDENGTFV NMTVSTFNWK DYVEDETHFY ILEGQRDALL CGNSSDAGQC PEGYICVKAG
RNPNYGYTSF DTFSWAFLSL FRLMTQDFWE NLYQLTLRAA GKTYMIFFVL VIFLGSFYLI
NLILAVVAMA YEEQNQATME EAEQKEAEFQ QMLEQLKKQQ EEAQATAAVA AASVASRDFS
GIGGLGELLE SSSEASKLSS KSAKERRNRR KKRRQKEMSE AEDKGDIDKF PKSESEDSIR
RKSFHFSTEG SQLTREKRFT SPHQSLLSIR GSLFSPRRNS RTSIFSFRGR AKDVGSENDF
ADDEHSTLED NESRRDSLFV PRRHGERRNS NISQASVSSR MVPALPVNGK MHSTVDCNGV
VSLVGGPSNL TSPTGQLIPE GTTTETEIRK RRLSSYQISM EMLEDSAARQ RAMSIASILT
NTMEELEESR QKCPPCWYRF ANTFLIWDCW SPWLKVKHVV NLVVMDPFVD LAITICIVLN
TLFMAMEHYP MTEQFSSVLS VGNLVFTGIF TAEMVLKIIA MDPYYYFQEG WNIFDGIIVS
LSLMELGLAN VEGLSVLRSF RLLRVFKLAK SWPTLNMLIK IIGNSVGALG NLTLVLAIIV
FIFAVVGMQL FGKSYKECVC KISSDCELPR WHMHDFFHSF LIVFRVLCGE WIETMWDCME
VAGQTMCLIV FMLVMVIGNL VVLNLFLALL LSSFSSDNLA ATDDDNEMNN LQIAVARIQK
GIDYVKKKMQ EFIQKAFVRK QKALEEIKAL EELNKKKDSC ISNHTAVEIS KDLNYLKDGN
GTTSGVGTGS SVEKYVIDEN DYMSFINNPG LTVTVPIAVG ESDFENLNTE EFSSESDMEE
SKQKLNASSS SEGSTVDIAP PGEGEQAEIE SEEALEPEAC FTEGCVQKFP CCQVSIEDGK
GKIWWNLRKT CYSIVEHNWF ETFIVFMILL SSGALAFEDI YIEQRKTIKT MLEYADKVFT
YIFILEMLLK WVAYGFQIYF TNAWCWLDFL IVDVSLVSLI ANALGYSELG AIKSLRTLRA
LRPLRALSRF EGMRVVVNAL VGAIPSIMNV LLVCLIFWLI FSIMGVNLFA GKFYHCVNTT
TGEMFDVSDV NNYTQCEELI KNNQSARWKN VKVNFDNVGA GYLALLQVAT FKGWMDIMYA
AVDSRDVEDQ PKYEDNLYMY LYFVIFIIFG SFFTLNLFIG VIIDNFNQQK KKIIFVLFLY
FGGQDIFMTE EQKKYYNAMK KLGSKKPQKP IPRPVNKFQG MVFDFVTKQV FDISIMILIC
LNMVTMMVET DDQSKEMETI LSRINLVFII LFTGECVLKL ISLRHYYFTI GWNIFDFVVV
ILSIVGMFLA EMIEKYFVS
//
