ID A0A091R5H3_9GRUI Unreviewed; 342 AA.
AC A0A091R5H3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=5' exonuclease Apollo {ECO:0000256|ARBA:ARBA00039555};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
DE AltName: Full=DNA cross-link repair 1B protein {ECO:0000256|ARBA:ARBA00041693};
DE AltName: Full=SNM1 homolog B {ECO:0000256|ARBA:ARBA00042738};
DE Flags: Fragment;
GN ORFNames=N332_11420 {ECO:0000313|EMBL:KFQ34731.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ34731.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ34731.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ34731.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
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DR EMBL; KK809838; KFQ34731.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091R5H3; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240:SF8; 5' EXONUCLEASE APOLLO; 1.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Exonuclease {ECO:0000313|EMBL:KFQ34731.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000313|EMBL:KFQ34731.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 138..172
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ34731.1"
FT NON_TER 342
FT /evidence="ECO:0000313|EMBL:KFQ34731.1"
SQ SEQUENCE 342 AA; 38602 MW; 2D93106606A75700 CRC64;
TGDFRYTSAM QIEPALRGRH IDRLYLDNTH CHPHRPLPSR QHATHLAAHV IRRHPQHQVV
IGMYSLGKET LLVDLAMEFS TWVVVSPRRL EQMRLEEGAG RIRAVDIAEI RGDTLVSWNM
LHPTIAILPT GRPVKVTHPN IYLVPYSDHS SFSELCEFVK WLKPCSVIPI VKGSMCQAYF
EKYLSSAPQA LPDLKIPKPM QESVQQQGKG KRQKPMCLLK RAVWHSVPRG VVYDSSEEYT
EKSEEVTDAK VLQQNCCESA SCSKGVCTCQ MGKEEGKEEL SGEQPGVRGA AGAVSQAPLS
DKHFPTALAE QYLLTPLHVL KHNSSQRFDE LVEDFFRRRE VS
//
