ID A0A091R8N1_9GRUI Unreviewed; 1736 AA.
AC A0A091R8N1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 41.
DE SubName: Full=Dedicator of cytokinesis protein 11 {ECO:0000313|EMBL:KFQ35821.1};
DE Flags: Fragment;
GN ORFNames=N332_12207 {ECO:0000313|EMBL:KFQ35821.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ35821.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ35821.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ35821.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR EMBL; KK811434; KFQ35821.1; -; Genomic_DNA.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08697; C2_Dock-D; 1.
DR CDD; cd13267; PH_DOCK-D; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR037809; C2_Dock-D.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR021816; DOCK_C/D_N.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR046769; DOCKER_Lobe_A.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR PANTHER; PTHR23317:SF81; DEDICATOR OF CYTOKINESIS PROTEIN 11; 1.
DR Pfam; PF06920; DHR-2_Lobe_A; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF11878; DOCK_C-D_N; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369}.
FT DOMAIN 131..238
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 605..783
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1574..1736
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 247..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1207..1226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ35821.1"
FT NON_TER 1736
FT /evidence="ECO:0000313|EMBL:KFQ35821.1"
SQ SEQUENCE 1736 AA; 198254 MW; 5CC58DE1C8F1DECB CRC64;
EKTKVVEPLD YENVILQRKV QIYSDPLRDL LIFPIEDVSI SVIGRQRRTV QSTVPEDALK
KAQSLFVKEC IKTYSSDWHV VNYKYEEYSG DFRMLPCKSF RPDKIPSHVF EIDEDFEKDE
DSSSLCSQKG GVIKQGWLHR ANVNSTITVT MKVFKRRYFY LSQLTDGSYI LNSYKDEKIS
KESKGCIFLD ACNDVVQCPK MRRYAFELKT IDKYSHYLAA ETEQEMEEWL VTLRKIIQSN
TESLMQEKKD AVESVQDDEP STQGKSESIM ESLERSMHPE LMKYGRETDQ LNKLSRNDGR
QNLFSFDPEV QRLDFSGIEP DVKPFEEKCS RRFVVCCQDF SLNLLAQLSD GPEGGPTNVE
PFFLSLALFD LKNNCKISAD FHVDLNPPSV RDMLLDNSAS GAEGTKGRSP GENLMHGVPE
SCLRYIKQGV FSVTDPHVEI FLVARVEKVL QGSITHCAEP YMKNSDPGKT AQKVHKVAKQ
VCSRLGQYRM PFGWAARPVF KDSQGTLDAE GKFSPLYKQD SSKLSNEDML KLLAEYKKPE
KTKLQVIPAQ LSIIIKDIPL DFANCVTASY IPIKPFGKSC EDIAVEVEEL VPEVVRYCYP
FTVYKNHLYV YPLHLKYENQ KVFAKARNIA LCVEFRDSDE ADARPLKCIY GKPGGHLLTT
NAYAAVLHHN QSPEFYDEIK IELPIHLHQK HHLLFTFYHV SCEINTKATS KKQDTVETQV
GYAWVPLLKD GRIVTLERHL PVSSNLPPGY LGLGDTESRK QPSVDAKWVD GAKPLFKIRI
HLDSTVYTQD MHLHKFFQYC QLVQAGAKEV PGELIKYLKC LHAMEIQVMI QFLPVILMQL
FRVLTNVTQE DEVAVNCTMV LLHIVSKCHE EGLDHYLRSF IKYVFRAEKP SVTQAKMTHE
ILVLSMATIL KQSADFLAIN KLLKYSWFFF EALAKSMAMY LLEENKIKLP RGQRFPDSYQ
HALHSLLLAI IPHVTIRYNE IPEESRNVNF SLANFLKRCL TFMDRGFVFN LINDYVSGFS
PKDPKLLVEY KFEFLQTICN HEHYIPLNLP MTFSKPKLQR VQDVNLEYSL TDEYCRHHFL
VGMLLREASV ALQDNYDIRY MAISVLKNLL IKHAFDNRYQ HKNQQAKIAQ LYLPLFGLLL
ENLQRVASRE ALYSCAAASS PASRDEFICS FASPSNRSSL ISDKDPACGA ALPNGHAIKR
EDSKGSLNSE GAASSPDQSE NVTYLGSSTR SSVSQCSRLD QFEIRTLLMC YLYIVKMISE
DILLAYWNKF SPQELINVLV LLEVCLFHFR YVGKRNIARV HDAWLSKHTG ADRKSQTMPA
LRSRAGGMQV RLQHLGSLET SFTLNHNAGT SEADIVHQAL LEGNIATEVC LTVLDTISFF
TQSFKTQLLS NDGHNPLMKK VFDIHLAFLK NGQSEAALKH VFASLRAFIS KFPSAFFKGR
VNMCAALCYE ILKCCTSKVS STRNEASALL YLLMRNNFEY TKRRTFLRTH LQIIIAVSQL
IADVALSGGT RFQDSLLIIN NFANSDRPMK ATAFPSEVKD LTKRIRTVLM ATAQMKEHEK
DPEMLIDLQY SLAKSYASTP ELRKTWLDSM AKIHVKNGDF SEAAMCYVHV AALVAEFLHR
KKLFPSGCTA FRKITPNIDE EGAMKEDGGM MDVHYSEEVL VELLEQCVDG LWKAERYETI
SEVSKLIIPI YEKRREFEKL TQLYRTLHGA YAKILEVMHT RKRLLGTFFR VAFYGQ
//
