ID A0A091RBR2_MERNU Unreviewed; 711 AA.
AC A0A091RBR2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00026121};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
GN ORFNames=N331_06448 {ECO:0000313|EMBL:KFQ36926.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ36926.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ36926.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ36926.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK716705; KFQ36926.1; -; Genomic_DNA.
DR RefSeq; XP_008946076.1; XM_008947828.1.
DR AlphaFoldDB; A0A091RBR2; -.
DR GeneID; 103780173; -.
DR KEGG; mnb:103780173; -.
DR CTD; 2182; -.
DR OrthoDB; 443463at2759; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd17639; LC_FACS_euk1; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43272:SF22; LONG-CHAIN-FATTY-ACID--COA LIGASE 4; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KFQ36926.1};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 117..531
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 711 AA; 79206 MW; D64AE514AF9D49E1 CRC64;
MKLRLEVCAV LLLPVYLLIS VYSMLVFIPW YFLTNAKKKK AMAKRLKAKP ISDKPGSPYR
SVTHLDSLAN INIPGADTLD KLFDHALAKF GKKDCLGTRE ILSEENEMQP NGKVFKKLIL
GTYRWLSYEE VNERVERLGS GLAALGLSPR STVVIFCETR AEWMIVALTC FKYNFPLVTL
YATLGEEAVT YGLNECGASY LVTSVELLES KLKTALPQVS CLKHIIYVDK KTVNKSEYPE
NVEIHSMQTI EELGAKPENS SIPPSRPVPT DLALVMYTSG STGRPKGVMM QHKNLIAGMT
GQCERIPGLG PKDTYIGYLP LAHVLELTAE ISCITYGCRI GYSSPLTLSD QSSKIKKGSK
GDCTVLKPTL MAAVPEIMDR IYKNVMSKVQ EMNYIQRTLF KIGYDYKLEQ IKRGYDAPLC
NVLLFKKVKA LLGGNIRMML SGGAPLSPQT QRFMNVCFCC PVGQGYGLTE TCGAGTITEV
ADYSTGRVGA PLICCEIKLR DWQEGGYTNK DKPNPRGEII IGGPNVSMGY FKNEEKTTEE
FSIDENGQRW FCTGDIGEFH PDGCLQIIDR KKDLVKLQAG EYVSLGKVEA ALKNCPLIDN
ICAYAKSDQS YVISFVVPNQ KKLTAVAEQK GISGTWADIC NNPTMEAEIL QEIKEVANKM
KLERFEIPIK VRLSPEPWTP ETGLVTDAFK LKRKELKNHY INDIERMYGG K
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